Lymphocytes influence intracranial aneurysm formation and rupture: role of extracellular matrix remodeling and phenotypic modulation of vascular smooth muscle cells.

Sawyer, David M; Pace, Lauren A; Pascale, Crissey L; Kutchin, Alexander C; O'Neill, Brannan E; Starke, Robert M; Dumont, Aaron S

Sawyer, David M; Pace, Lauren A; Pascale, Crissey L; Kutchin, Alexander C; O'Neill, Brannan E; Starke, Robert M; Dumont, Aaron S.

Afiliación

Sawyer DM; Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, 131 S. Robertson St. Ste. 1300, 8047, New Orleans, LA, 70112, USA.
Pace LA; Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, 131 S. Robertson St. Ste. 1300, 8047, New Orleans, LA, 70112, USA.
Pascale CL; Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, 131 S. Robertson St. Ste. 1300, 8047, New Orleans, LA, 70112, USA.
Kutchin AC; Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, 131 S. Robertson St. Ste. 1300, 8047, New Orleans, LA, 70112, USA.
O'Neill BE; Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, 131 S. Robertson St. Ste. 1300, 8047, New Orleans, LA, 70112, USA.
Starke RM; Department of Neurosurgery, University of Miami, Miami, FL, USA.
Dumont AS; Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, 131 S. Robertson St. Ste. 1300, 8047, New Orleans, LA, 70112, USA. adumont2@tulane.edu.

J Neuroinflammation ; 13(1): 185, 2016 07 14.

Article en En | MEDLINE | ID: mdl-27416931

Asunto(s)

Aneurisma Roto/patología; Regulación de la Expresión Génica/fisiología; Aneurisma Intracraneal/patología; Linfocitos/fisiología; Músculo Liso Vascular/metabolismo; Animales; Antígenos CD/metabolismo; Antígenos de Diferenciación Mielomonocítica/metabolismo; Modelos Animales de Enfermedad; Citometría de Flujo; Regulación de la Expresión Génica/genética; Proteínas de Homeodominio/genética; Proteínas de Homeodominio/metabolismo; Interleucina-6/metabolismo; Aneurisma Intracraneal/genética; Metaloproteinasa 2 de la Matriz/metabolismo; Metaloproteinasa 9 de la Matriz/metabolismo; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Miosinas del Músculo Liso/metabolismo

Palabras clave

Cerebral aneurysm; Inflammation; Interleukin-6; Leukocyte; Matrix metalloproteinase 2; Matrix metalloproteinase 9; Myosin heavy chain; Rag1 mice; Subarachnoid hemorrhage

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos / Aneurisma Intracraneal / Regulación de la Expresión Génica / Aneurisma Roto / Músculo Liso Vascular Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2016 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google