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A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics.
Tschapalda, Kirsten; Zhang, Ya-Qin; Liu, Li; Golovnina, Kseniya; Schlemper, Thomas; Eichmann, Thomas O; Lal-Nag, Madhu; Sreenivasan, Urmila; McLenithan, John; Ziegler, Slava; Sztalryd, Carole; Lass, Achim; Auld, Douglas; Oliver, Brian; Waldmann, Herbert; Li, Zhuyin; Shen, Min; Boxer, Matthew B; Beller, Mathias.
Afiliación
  • Tschapalda K; Systems Biology of Lipid Metabolism, Heinrich Heine University Düsseldorf, Germany; Institute for Mathematical Modeling of Biological Systems, Heinrich Heine University Düsseldorf, Germany; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany; Department of
  • Zhang YQ; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, USA.
  • Liu L; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, USA.
  • Golovnina K; National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, USA.
  • Schlemper T; Systems Biology of Lipid Metabolism, Heinrich Heine University Düsseldorf, Germany; Institute for Mathematical Modeling of Biological Systems, Heinrich Heine University Düsseldorf, Germany.
  • Eichmann TO; Institute of Molecular Biosciences, University of Graz, Austria.
  • Lal-Nag M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, USA.
  • Sreenivasan U; Department of Medicine, Division of Endocrinology University of Maryland School of Medicine, USA.
  • McLenithan J; Department of Medicine, Division of Endocrinology University of Maryland School of Medicine, USA.
  • Ziegler S; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany.
  • Sztalryd C; Department of Medicine, Division of Endocrinology University of Maryland School of Medicine, USA; Baltimore VA Medical Center, VA Research Service, Geriatric Research, Education and Clinical Center (GRECC) and VA Maryland Health Care System, Department of Medicine, Division of Endocrinology Universi
  • Lass A; Institute of Molecular Biosciences, University of Graz, Austria.
  • Auld D; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, USA.
  • Oliver B; National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, USA.
  • Waldmann H; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany.
  • Li Z; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, USA.
  • Shen M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, USA.
  • Boxer MB; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, USA.
  • Beller M; Systems Biology of Lipid Metabolism, Heinrich Heine University Düsseldorf, Germany; Institute for Mathematical Modeling of Biological Systems, Heinrich Heine University Düsseldorf, Germany. Electronic address: mathias.beller@hhu.de.
EBioMedicine ; 8: 49-59, 2016 Jun.
Article en En | MEDLINE | ID: mdl-27428418
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Genómica / Inhibidores Enzimáticos / Diacilglicerol O-Acetiltransferasa Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Female / Humans / Male Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Genómica / Inhibidores Enzimáticos / Diacilglicerol O-Acetiltransferasa Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Female / Humans / Male Idioma: En Año: 2016 Tipo del documento: Article