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Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease.
Alexopoulou, Zoi; Lang, Johannes; Perrett, Rebecca M; Elschami, Myriam; Hurry, Madeleine E D; Kim, Hyoung Tae; Mazaraki, Dimitra; Szabo, Aron; Kessler, Benedikt M; Goldberg, Alfred Lewis; Ansorge, Olaf; Fulga, Tudor A; Tofaris, George K.
Afiliación
  • Alexopoulou Z; Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom;
  • Lang J; Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom;
  • Perrett RM; Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom;
  • Elschami M; Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom;
  • Hurry ME; Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom;
  • Kim HT; Department of Cell Biology, Harvard Medical School, Boston, MA 02115;
  • Mazaraki D; Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom;
  • Szabo A; Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom;
  • Kessler BM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, United Kingdom.
  • Goldberg AL; Department of Cell Biology, Harvard Medical School, Boston, MA 02115;
  • Ansorge O; Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom;
  • Fulga TA; Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom;
  • Tofaris GK; Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom; george.tofaris@ndcn.ox.ac.uk.
Proc Natl Acad Sci U S A ; 113(32): E4688-97, 2016 08 09.
Article en En | MEDLINE | ID: mdl-27444016
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Enfermedad por Cuerpos de Lewy / Ubiquitina Tiolesterasa / Alfa-Sinucleína / Ubiquitinación / Complejos de Clasificación Endosomal Requeridos para el Transporte Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Año: 2016 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Enfermedad por Cuerpos de Lewy / Ubiquitina Tiolesterasa / Alfa-Sinucleína / Ubiquitinación / Complejos de Clasificación Endosomal Requeridos para el Transporte Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Año: 2016 Tipo del documento: Article