Antioxidative therapy in an ex vivo human cartilage trauma-model: attenuation of trauma-induced cell loss and ECM-destructive enzymes by N-acetyl cysteine.

Riegger, J; Joos, H; Palm, H G; Friemert, B; Reichel, H; Ignatius, A; Brenner, R E

Antioxidative therapy in an ex vivo human cartilage trauma-model: attenuation of trauma-induced cell loss and ECM-destructive enzymes by N-acetyl cysteine.

Riegger, J; Joos, H; Palm, H G; Friemert, B; Reichel, H; Ignatius, A; Brenner, R E.

Afiliación

Riegger J; Division for Biochemistry of Joint and Connective Tissue Diseases, Department of Orthopedics, University of Ulm, Ulm, Germany.
Joos H; Division for Biochemistry of Joint and Connective Tissue Diseases, Department of Orthopedics, University of Ulm, Ulm, Germany.
Palm HG; Department of Orthopedics and Trauma Surgery, German Armed Forces Hospital of Ulm, Ulm, Germany.
Friemert B; Department of Orthopedics and Trauma Surgery, German Armed Forces Hospital of Ulm, Ulm, Germany.
Reichel H; Department of Orthopedics, University of Ulm, Ulm, Germany.
Ignatius A; Institute of Orthopedic Research and Biomechanics, University of Ulm, Ulm, Germany.
Brenner RE; Division for Biochemistry of Joint and Connective Tissue Diseases, Department of Orthopedics, University of Ulm, Ulm, Germany. Electronic address: rolf.brenner@uni-ulm.de.

Osteoarthritis Cartilage ; 24(12): 2171-2180, 2016 12.

Article en En | MEDLINE | ID: mdl-27514995

Asunto(s)

Cartílago; Acetilcisteína; Condrocitos; Matriz Extracelular; Humanos; Proteoglicanos

Palabras clave

Cell protection; Chondroprotection; ECM degradation; Mechanical loading; N-acetyl cysteine; Posttraumatic osteoarthritis

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cartílago Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2016 Tipo del documento: Article

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