Crystal structure and DNA binding activity of a PadR family transcription regulator from hypervirulent Clostridium difficile R20291.

Isom, Catherine E; Menon, Smita K; Thomas, Leonard M; West, Ann H; Richter-Addo, George B; Karr, Elizabeth A

Isom, Catherine E; Menon, Smita K; Thomas, Leonard M; West, Ann H; Richter-Addo, George B; Karr, Elizabeth A.

Afiliación

Isom CE; Price Family Foundation Institute of Structural Biology and Department of Microbiology and Plant Biology, University of Oklahoma, 770 Van Vleet Oval, Norman, OK, 73019, USA.
Menon SK; Price Family Foundation Institute of Structural Biology and Department of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, OK, 73019, USA.
Thomas LM; Price Family Foundation Institute of Structural Biology and Department of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, OK, 73019, USA.
West AH; Price Family Foundation Institute of Structural Biology and Department of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, OK, 73019, USA.
Richter-Addo GB; Price Family Foundation Institute of Structural Biology and Department of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, OK, 73019, USA.
Karr EA; Price Family Foundation Institute of Structural Biology and Department of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, OK, 73019, USA.

BMC Microbiol ; 16(1): 231, 2016 Oct 04.

Article en En | MEDLINE | ID: mdl-27716049

Asunto(s)

Proteínas Bacterianas/química; Clostridioides difficile/metabolismo; Proteínas de Unión al ADN/química; Secuencia de Aminoácidos; Proteínas Bacterianas/genética; Proteínas Bacterianas/metabolismo; Secuencia de Bases; Clostridioides difficile/química; Clostridioides difficile/genética; Cristalografía por Rayos X; ADN Bacteriano/genética; ADN Bacteriano/metabolismo; Proteínas de Unión al ADN/genética; Proteínas de Unión al ADN/metabolismo; Farmacorresistencia Microbiana; Ensayo de Cambio de Movilidad Electroforética; Modelos Moleculares; Mutación; Motivos de Nucleótidos; Regiones Promotoras Genéticas; Unión Proteica; Estructura Secundaria de Proteína; Alineación de Secuencia

Palabras clave

Bacteria; Clostridium difficile; PadR; Stress response; Structural biology; Transcription regulation

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Clostridioides difficile / Proteínas de Unión al ADN Tipo de estudio: Prognostic_studies Idioma: En Año: 2016 Tipo del documento: Article

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