Comparative toxicity and biodistribution assessments in rats following subchronic oral exposure to copper nanoparticles and microparticles.

Lee, In-Chul; Ko, Je-Won; Park, Sung-Hyeuk; Shin, Na-Rae; Shin, In-Sik; Moon, Changjong; Kim, Je-Hein; Kim, Hyoung-Chin; Kim, Jong-Choon

Lee, In-Chul; Ko, Je-Won; Park, Sung-Hyeuk; Shin, Na-Rae; Shin, In-Sik; Moon, Changjong; Kim, Je-Hein; Kim, Hyoung-Chin; Kim, Jong-Choon.

Afiliación

Lee IC; College of Veterinary Medicine BK21 Plus Project Team, Chonnam National University, Gwangju, 61186, Republic of Korea.
Ko JW; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup, 56212, Republic of Korea.
Park SH; College of Veterinary Medicine BK21 Plus Project Team, Chonnam National University, Gwangju, 61186, Republic of Korea.
Shin NR; College of Veterinary Medicine BK21 Plus Project Team, Chonnam National University, Gwangju, 61186, Republic of Korea.
Shin IS; College of Veterinary Medicine BK21 Plus Project Team, Chonnam National University, Gwangju, 61186, Republic of Korea.
Moon C; College of Veterinary Medicine BK21 Plus Project Team, Chonnam National University, Gwangju, 61186, Republic of Korea.
Kim JH; College of Veterinary Medicine BK21 Plus Project Team, Chonnam National University, Gwangju, 61186, Republic of Korea.
Kim HC; Gyeongnam Department of Environment & Toxicology, Korea Institute of Toxicology, Gyeongnam, 52834, Republic of Korea.
Kim JC; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, ChungBuk, 28116, Republic of Korea. hckim@kribb.re.kr.

Part Fibre Toxicol ; 13(1): 56, 2016 10 28.

Article en En | MEDLINE | ID: mdl-27788687

Asunto(s)

Cobre/farmacocinética; Cobre/toxicidad; Nanopartículas del Metal/toxicidad; Administración Oral; Animales; Relación Dosis-Respuesta a Droga; Masculino; Microscopía Electrónica de Rastreo; Microesferas; Tamaño de los Órganos/efectos de los fármacos; Ratas; Ratas Sprague-Dawley; Distribución Tisular; Pruebas de Toxicidad Subcrónica

Palabras clave

Biodistribution; Comparative toxicity; Copper microparticles; Copper nanoparticles

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cobre / Nanopartículas del Metal Límite: Animals Idioma: En Año: 2016 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cobre / Nanopartículas del Metal Límite: Animals Idioma: En Año: 2016 Tipo del documento: Article