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Trametinib Drives T-cell-Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis.
Allegrezza, Michael J; Rutkowski, Melanie R; Stephen, Tom L; Svoronos, Nikolaos; Perales-Puchalt, Alfredo; Nguyen, Jenny M; Payne, Kyle K; Singhal, Sunil; Eruslanov, Evgeniy B; Tchou, Julia; Conejo-Garcia, Jose R.
Afiliación
  • Allegrezza MJ; Tumor Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, Pennsylvania.
  • Rutkowski MR; Tumor Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, Pennsylvania.
  • Stephen TL; Tumor Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, Pennsylvania.
  • Svoronos N; Tumor Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, Pennsylvania.
  • Perales-Puchalt A; Tumor Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, Pennsylvania.
  • Nguyen JM; Tumor Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, Pennsylvania.
  • Payne KK; Tumor Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, Pennsylvania.
  • Singhal S; Division of Thoracic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Eruslanov EB; Division of Thoracic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Tchou J; Division of Endocrine and Oncologic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Conejo-Garcia JR; Tumor Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, Pennsylvania. jrconejo@wistar.org.
Cancer Res ; 76(21): 6253-6265, 2016 11 01.
Article en En | MEDLINE | ID: mdl-27803104
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piridonas / Pirimidinonas / Linfocitos T / Proteínas Proto-Oncogénicas p21(ras) / Mielopoyesis / Mutación / Neoplasias / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Año: 2016 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piridonas / Pirimidinonas / Linfocitos T / Proteínas Proto-Oncogénicas p21(ras) / Mielopoyesis / Mutación / Neoplasias / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Año: 2016 Tipo del documento: Article