How Presentation of Drug Detection Results Changed Reports of Product Adherence in South Africa, Uganda and Zimbabwe.
AIDS Behav
; 22(3): 877-886, 2018 03.
Article
en En
| MEDLINE
| ID: mdl-28110473
ABSTRACT
Accurate estimates of study product use are critical to understanding and addressing adherence challenges in HIV prevention trials. The VOICE trial exposed a significant gap between self-reported adherence and drug detection. The VOICE-D qualitative study was designed to better understand non-adherence during VOICE, and was conducted in 2 stages before (stage 1) and after (stage 2) drug detection results were provided to participants. Transcripts from 44 women who participated in both stages were analysed to understand the effect of presenting drug detection data on narratives of product use. Thirty-six women reported high adherence in stage 1, yet admitted non-use in stage 2, three reported high adherence in both stages (contrary to their drug detection results) and five had consistent responses across both stages and drug results. Presenting objective measures of use may facilitate more accurate product use reporting and should be evaluated in future prevention trials.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Infecciones por VIH
/
Fármacos Anti-VIH
/
Cumplimiento de la Medicación
/
Profilaxis Pre-Exposición
Tipo de estudio:
Diagnostic_studies
/
Qualitative_research
Límite:
Adult
/
Female
/
Humans
País/Región como asunto:
Africa
Idioma:
En
Año:
2018
Tipo del documento:
Article