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Human NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase.
Liu, Xiao; Pichulik, Tica; Wolz, Olaf-Oliver; Dang, Truong-Minh; Stutz, Andrea; Dillen, Carly; Delmiro Garcia, Magno; Kraus, Helene; Dickhöfer, Sabine; Daiber, Ellen; Münzenmayer, Lisa; Wahl, Silke; Rieber, Nikolaus; Kümmerle-Deschner, Jasmin; Yazdi, Amir; Franz-Wachtel, Mirita; Macek, Boris; Radsak, Markus; Vogel, Sebastian; Schulte, Berit; Walz, Juliane Sarah; Hartl, Dominik; Latz, Eicke; Stilgenbauer, Stephan; Grimbacher, Bodo; Miller, Lloyd; Brunner, Cornelia; Wolz, Christiane; Weber, Alexander N R.
Afiliación
  • Liu X; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Pichulik T; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Wolz OO; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Dang TM; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Stutz A; Institute of Innate Immunity, University Hospital Bonn, Bonn, Germany.
  • Dillen C; Department of Dermatology, Johns Hopkins University, Baltimore, Md.
  • Delmiro Garcia M; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Kraus H; Centre of Chronic Immunodeficiency, University Hospital Freiburg, Freiburg, Germany.
  • Dickhöfer S; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Daiber E; Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany.
  • Münzenmayer L; Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany.
  • Wahl S; Proteome Center Tübingen, University of Tübingen, Tübingen, Germany.
  • Rieber N; Department of Pediatrics I, University Hospital Tübingen, Tübingen, Germany.
  • Kümmerle-Deschner J; Department of Pediatrics I, University Hospital Tübingen, Tübingen, Germany.
  • Yazdi A; Department of Dermatology, University Hospital Tübingen, Tübingen, Germany.
  • Franz-Wachtel M; Proteome Center Tübingen, University of Tübingen, Tübingen, Germany.
  • Macek B; Proteome Center Tübingen, University of Tübingen, Tübingen, Germany.
  • Radsak M; Medical Hospital III, University Hospital Mainz, Mainz, Germany.
  • Vogel S; Department of Cardiology and Cardiovascular Diseases, University Hospital Tübingen, Tübingen, Germany.
  • Schulte B; Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany.
  • Walz JS; Medical Hospital II (Department of Hematology and Oncology), University Hospital Tübingen, Tübingen, Germany.
  • Hartl D; Department of Pediatrics I, University Hospital Tübingen, Tübingen, Germany.
  • Latz E; Institute of Innate Immunity, University Hospital Bonn, Bonn, Germany; Division of Infectious Diseases & Immunology, University of Massachusetts, Worcester, Mass.
  • Stilgenbauer S; Department of Internal Medicine III, Ulm University Hospital, Ulm, Germany.
  • Grimbacher B; Centre of Chronic Immunodeficiency, University Hospital Freiburg, Freiburg, Germany.
  • Miller L; Department of Dermatology, Johns Hopkins University, Baltimore, Md.
  • Brunner C; Department of Otorhinolaryngology, Ulm University Medical Center, Ulm, Germany.
  • Wolz C; Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany.
  • Weber ANR; Interfaculty Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany. Electronic address: alexander.weber@uni.tuebingen.de.
J Allergy Clin Immunol ; 140(4): 1054-1067.e10, 2017 Oct.
Article en En | MEDLINE | ID: mdl-28216434

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Infecciones Estafilocócicas / Staphylococcus aureus / Proteínas Tirosina Quinasas / Agammaglobulinemia / Enfermedades Genéticas Ligadas al Cromosoma X / Síndromes Periódicos Asociados a Criopirina / Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Infecciones Estafilocócicas / Staphylococcus aureus / Proteínas Tirosina Quinasas / Agammaglobulinemia / Enfermedades Genéticas Ligadas al Cromosoma X / Síndromes Periódicos Asociados a Criopirina / Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article