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SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling.
Blattner, Mirjam; Liu, Deli; Robinson, Brian D; Huang, Dennis; Poliakov, Anton; Gao, Dong; Nataraj, Srilakshmi; Deonarine, Lesa D; Augello, Michael A; Sailer, Verena; Ponnala, Lalit; Ittmann, Michael; Chinnaiyan, Arul M; Sboner, Andrea; Chen, Yu; Rubin, Mark A; Barbieri, Christopher E.
Afiliación
  • Blattner M; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.
  • Liu D; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; Department of Urology, Weill Cornell Medicine, New York, NY 10065, USA; HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 1006
  • Robinson BD; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Huang D; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.
  • Poliakov A; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Gao D; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
  • Nataraj S; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.
  • Deonarine LD; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.
  • Augello MA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; Department of Urology, Weill Cornell Medicine, New York, NY 10065, USA.
  • Sailer V; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Ponnala L; Computational Biology Service Unit, Cornell University, Ithaca, NY 14853, USA.
  • Ittmann M; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Chinnaiyan AM; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Departments of Pathology and Urology, and Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA.
  • Sboner A; HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA; Englander Institute for Precision Medicine of Weill Cornell Medicine, and New York-Presbyterian Hospital, New York, NY 10065, USA.
  • Chen Y; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Medicine, MSKCC, New York, NY 10065, USA.
  • Rubin MA; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; Department of Urology, Weill Cornell Medicine, New York, NY 10065, USA; Englander Institute for Precision Medicine
  • Barbieri CE; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; Department of Urology, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: chb9074@med.cornell.edu.
Cancer Cell ; 31(3): 436-451, 2017 03 13.
Article en En | MEDLINE | ID: mdl-28292441

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Proteínas Represoras / Proteínas Nucleares / Transducción de Señal / Receptores Androgénicos / Fosfatidilinositol 3-Quinasas / Serina-Treonina Quinasas TOR / Mutación Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Proteínas Represoras / Proteínas Nucleares / Transducción de Señal / Receptores Androgénicos / Fosfatidilinositol 3-Quinasas / Serina-Treonina Quinasas TOR / Mutación Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Año: 2017 Tipo del documento: Article