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High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock-in mice across multiple genetic backgrounds.
Ament, Seth A; Pearl, Jocelynn R; Grindeland, Andrea; St Claire, Jason; Earls, John C; Kovalenko, Marina; Gillis, Tammy; Mysore, Jayalakshmi; Gusella, James F; Lee, Jong-Min; Kwak, Seung; Howland, David; Lee, Min Young; Baxter, David; Scherler, Kelsey; Wang, Kai; Geman, Donald; Carroll, Jeffrey B; MacDonald, Marcy E; Carlson, George; Wheeler, Vanessa C; Price, Nathan D; Hood, Leroy E.
Afiliación
  • Ament SA; Institute for Systems Biology, Seattle, WA, USA.
  • Pearl JR; Institute for Genome Sciences and Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Grindeland A; Institute for Systems Biology, Seattle, WA, USA.
  • St Claire J; Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, WA, USA.
  • Earls JC; McLaughlin Research Institute, Great Falls, MT, USA.
  • Kovalenko M; Center for Human Genetic Research, Massachusetts General Hospital, Department of Neurology, Harvard Medical School, Boston, MA, USA.
  • Gillis T; Institute for Systems Biology, Seattle, WA, USA.
  • Mysore J; Department of Computer Science, University of Washington, Seattle, WA, USA.
  • Gusella JF; Center for Human Genetic Research, Massachusetts General Hospital, Department of Neurology, Harvard Medical School, Boston, MA, USA.
  • Lee JM; Center for Human Genetic Research, Massachusetts General Hospital, Department of Neurology, Harvard Medical School, Boston, MA, USA.
  • Kwak S; Center for Human Genetic Research, Massachusetts General Hospital, Department of Neurology, Harvard Medical School, Boston, MA, USA.
  • Howland D; Center for Human Genetic Research, Massachusetts General Hospital, Department of Neurology, Harvard Medical School, Boston, MA, USA.
  • Lee MY; Center for Human Genetic Research, Massachusetts General Hospital, Department of Neurology, Harvard Medical School, Boston, MA, USA.
  • Baxter D; CHDI Management/CHDI Foundation, Princeton, NJ, USA.
  • Scherler K; CHDI Management/CHDI Foundation, Princeton, NJ, USA.
  • Wang K; Institute for Systems Biology, Seattle, WA, USA.
  • Geman D; Institute for Systems Biology, Seattle, WA, USA.
  • Carroll JB; Institute for Systems Biology, Seattle, WA, USA.
  • MacDonald ME; Institute for Systems Biology, Seattle, WA, USA.
  • Carlson G; Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA.
  • Wheeler VC; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.
  • Price ND; Center for Human Genetic Research, Massachusetts General Hospital, Department of Neurology, Harvard Medical School, Boston, MA, USA.
  • Hood LE; McLaughlin Research Institute, Great Falls, MT, USA.
Hum Mol Genet ; 26(5): 913-922, 2017 03 01.
Article en En | MEDLINE | ID: mdl-28334820
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Cuerpo Estriado / Expansión de Repetición de Trinucleótido / Proteína Huntingtina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Cuerpo Estriado / Expansión de Repetición de Trinucleótido / Proteína Huntingtina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article