Pharmacokinetics and Placental Transfer of Elvitegravir, Dolutegravir, and Other Antiretrovirals during Pregnancy.

Rimawi, Bassam H; Johnson, Erica; Rajakumar, Augustine; Tao, Sijia; Jiang, Yong; Gillespie, Scott; Schinazi, Raymond F; Mirochnick, Mark; Badell, Martina L; Chakraborty, Rana

Rimawi, Bassam H; Johnson, Erica; Rajakumar, Augustine; Tao, Sijia; Jiang, Yong; Gillespie, Scott; Schinazi, Raymond F; Mirochnick, Mark; Badell, Martina L; Chakraborty, Rana.

Afiliación

Rimawi BH; Emory University, School of Medicine, Atlanta, Georgia, USA bassamrimawi@yahoo.com.
Johnson E; Department of Gynecology and Obstetrics, Division of Maternal Fetal Medicine, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Rajakumar A; Emory University, School of Medicine, Atlanta, Georgia, USA.
Tao S; Department of Pediatrics, Division of Infectious Diseases, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Jiang Y; Emory University, School of Medicine, Atlanta, Georgia, USA.
Gillespie S; Department of Gynecology and Obstetrics, Division of Maternal Fetal Medicine, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Schinazi RF; Emory University, School of Medicine, Atlanta, Georgia, USA.
Mirochnick M; Department of Pediatrics, Center for AIDS Research, Laboratory of Biochemical Pharmacology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Badell ML; Emory University, School of Medicine, Atlanta, Georgia, USA.
Chakraborty R; Department of Pediatrics, Center for AIDS Research, Laboratory of Biochemical Pharmacology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA.

Antimicrob Agents Chemother ; 61(6)2017 06.

Article en En | MEDLINE | ID: mdl-28348149

Asunto(s)

Antirretrovirales/farmacocinética; Compuestos Heterocíclicos con 3 Anillos/farmacocinética; Placenta/metabolismo; Quinolonas/farmacocinética; Adolescente; Adulto; Femenino; Infecciones por VIH/tratamiento farmacológico; Infecciones por VIH/metabolismo; VIH-1/efectos de los fármacos; VIH-1/patogenicidad; Humanos; Oxazinas; Piperazinas; Embarazo; Piridonas; Adulto Joven

Palabras clave

HIV-1; dolutegravir; elvitegravir; integrase inhibitors; pharmacokinetics; placental transfer; pregnancy

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Placenta / Quinolonas / Antirretrovirales / Compuestos Heterocíclicos con 3 Anillos Límite: Adolescent / Adult / Female / Humans / Pregnancy Idioma: En Año: 2017 Tipo del documento: Article

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