Application of spin echoes in the regime of weak dephasing to T1 -mapping of the lung.
Magn Reson Med
; 79(2): 960-967, 2018 02.
Article
en En
| MEDLINE
| ID: mdl-28419591
ABSTRACT
PURPOSE:
This work presents an approach to mapping the entire lung's proton density and T1 within a single breath-hold and analyzes the apparent T1 when exciting with a spin echo generating pulse in comparison to a standard gradient echo acquisition.METHODS:
An inversion-recovery SNAPSHOT-FLASH sequence with a stack-of-stars k-space readout with a golden angle increment was modified to use a spin echo generating radiofrequency-pulse for excitation. Data of five volunteers were acquired on a 3T scanner and image reconstruction was performed by an iterative algorithm adopted from MR-Fingerprinting.RESULTS:
The feasibility of acquiring quantitative maps of the entire lung with a resolution of 5 × 5 × 10 mm within 7.5 s is demonstrated. It is shown that the proposed spin echo forming radiofrequency-pulse increases the apparent proton density compared to a rectangular pulse. Further, the apparent T1 is reduced in the spin echo case compared to the gradient echo sequence.CONCLUSION:
The proposed spin echo based method results in T1 maps that are comparable to the ones that were acquired with ultra-short echo time sequences elsewhere. The T1 shortening is believed to originate from increased signal contributions of the extra vascular compartment, which has a short T2∗ and T1 . Magn Reson Med 79960-967, 2018. © 2017 International Society for Magnetic Resonance in Medicine.Palabras clave
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1
Banco de datos:
MEDLINE
Asunto principal:
Procesamiento de Imagen Asistido por Computador
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Pulmón
Límite:
Adult
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Female
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Humans
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Male
Idioma:
En
Año:
2018
Tipo del documento:
Article