Arsenic-mediated hyperpigmentation in skin via NF-kappa B/endothelin-1 signaling in an originally developed hairless mouse model.

Yajima, Ichiro; Kumasaka, Mayuko Y; Iida, Machiko; Oshino, Reina; Tanihata, Hiroko; Al Hossain, Aeorangajeb; Ohgami, Nobutaka; Kato, Masashi

Yajima, Ichiro; Kumasaka, Mayuko Y; Iida, Machiko; Oshino, Reina; Tanihata, Hiroko; Al Hossain, Aeorangajeb; Ohgami, Nobutaka; Kato, Masashi.

Afiliación

Yajima I; Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan.
Kumasaka MY; Unit of Environmental Health Sciences, Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, 487-8501, Japan.
Iida M; Voluntary Body for International Health Care in Universities, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan.
Oshino R; Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan.
Tanihata H; Unit of Environmental Health Sciences, Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, 487-8501, Japan.
Al Hossain A; Voluntary Body for International Health Care in Universities, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan.
Ohgami N; Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan.
Kato M; Unit of Environmental Health Sciences, Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai, Aichi, 487-8501, Japan.

Arch Toxicol ; 91(11): 3507-3516, 2017 Nov.

Article en En | MEDLINE | ID: mdl-28470405

Asunto(s)

Arsénico/toxicidad; Endotelina-1/metabolismo; Hiperpigmentación/inducido químicamente; FN-kappa B/metabolismo; Animales; Línea Celular; Modelos Animales de Enfermedad; Agua Potable/efectos adversos; Células Epidérmicas; Epidermis/efectos de los fármacos; Epidermis/metabolismo; Homocigoto; Humanos; Hiperpigmentación/metabolismo; Queratinocitos/efectos de los fármacos; Queratinocitos/metabolismo; Queratinocitos/patología; Melanocitos/efectos de los fármacos; Melanocitos/metabolismo; Ratones Pelados; Receptor de Endotelina B/genética; Receptor de Endotelina B/metabolismo

Palabras clave

Arsenic; Endothelin-1; Hyperpigmentation; Model mouse; NF-kB

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Arsénico / FN-kappa B / Hiperpigmentación / Endotelina-1 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article

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