Influence of quercetin on the interaction of gliclazide with human serum albumin - spectroscopic and docking approaches.

Kameníková, Miroslava; Furtmüller, Paul Georg; Klacsová, Mária; Lopez-Guzman, Arturo; Toca-Herrera, José Luis; Vitkovská, Anika; Devínsky, Ferdinand; Mucaji, Pavel; Nagy, Milan

Kameníková, Miroslava; Furtmüller, Paul Georg; Klacsová, Mária; Lopez-Guzman, Arturo; Toca-Herrera, José Luis; Vitkovská, Anika; Devínsky, Ferdinand; Mucaji, Pavel; Nagy, Milan.

Afiliación

Kameníková M; Department of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovakia.
Furtmüller PG; Department of Chemistry, University of Natural Resources and Life Sciences, Vienna, Austria.
Klacsová M; Department of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovakia.
Lopez-Guzman A; Department of Nanobiotechnology, University of Natural Resources and Life Sciences, Vienna, Austria.
Toca-Herrera JL; Department of Nanobiotechnology, University of Natural Resources and Life Sciences, Vienna, Austria.
Vitkovská A; Department of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovakia.
Devínsky F; Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovakia.
Mucaji P; Department of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovakia.
Nagy M; Department of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovakia.

Luminescence ; 32(7): 1203-1211, 2017 Nov.

Article en En | MEDLINE | ID: mdl-28513070

Asunto(s)

Gliclazida/farmacología; Quercetina/farmacología; Albúmina Sérica Humana/química; Albúmina Sérica Humana/metabolismo; Unión Competitiva; Dicroismo Circular; Interacciones Farmacológicas; Gliclazida/metabolismo; Simulación del Acoplamiento Molecular; Conformación Proteica; Quercetina/metabolismo; Espectrometría de Fluorescencia; Espectroscopía Infrarroja por Transformada de Fourier

Palabras clave

circular dichroism; fluorescence; gliclazide; human serum albumin; quercetin

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quercetina / Albúmina Sérica Humana / Gliclazida Idioma: En Año: 2017 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quercetina / Albúmina Sérica Humana / Gliclazida Idioma: En Año: 2017 Tipo del documento: Article