Sensitive LC-MS/MS Method for the Simultaneous Determination of Bendamustine and its Active Metabolite, Î³-Hydroxybendamustine in Small Volume Mice and Dog Plasma and its Application to a Pharmacokinetic Study in Mice and Dogs.

Chandrashekar, Devaraj V; Suresh, Ponnayyan S; Kumar, Rajnish; Bhamidipati, Ravi Kanth; Mullangi, Ramesh; Richter, Wolfgang; Srinivas, Nuggehally R

Chandrashekar, Devaraj V; Suresh, Ponnayyan S; Kumar, Rajnish; Bhamidipati, Ravi Kanth; Mullangi, Ramesh; Richter, Wolfgang; Srinivas, Nuggehally R.

Afiliación

Chandrashekar DV; Drug Metabolism and Pharmacokinetics, Jubilant Biosys Ltd, Yeshwanthpur, Bangalore, India.
Suresh PS; Drug Metabolism and Pharmacokinetics, Jubilant Biosys Ltd, Yeshwanthpur, Bangalore, India.
Kumar R; Drug Metabolism and Pharmacokinetics, Jubilant Biosys Ltd, Yeshwanthpur, Bangalore, India.
Bhamidipati RK; Drug Metabolism and Pharmacokinetics, Jubilant Biosys Ltd, Yeshwanthpur, Bangalore, India.
Mullangi R; Drug Metabolism and Pharmacokinetics, Jubilant Biosys Ltd, Yeshwanthpur, Bangalore, India.
Richter W; TUBE Pharmaceuticals GmbH, Wien, Austria.
Srinivas NR; Suramus Bio, Drug Development, J. P. Nagar, Bangalore, India.

Drug Res (Stuttg) ; 67(9): 497-508, 2017 Sep.

Article en En | MEDLINE | ID: mdl-28561238

Asunto(s)

Antineoplásicos Alquilantes/sangre; Clorhidrato de Bendamustina/análogos & derivados; Cromatografía Liquida/métodos; Espectrometría de Masas en Tándem/métodos; Animales; Clorhidrato de Bendamustina/sangre; Perros; Extracción Líquido-Líquido; Masculino; Ratones; Ratones Endogámicos BALB C; Reproducibilidad de los Resultados

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Cromatografía Liquida / Antineoplásicos Alquilantes / Espectrometría de Masas en Tándem / Clorhidrato de Bendamustina Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Año: 2017 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google