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Synthesis and pharmacological evaluation of novel selective MOR agonist 6ß-pyridinyl amidomorphines exhibiting long-lasting antinociception.
Urai, Ákos; Váradi, András; Szocs, Levente; Komjáti, Balázs; Le Rouzic, Valerie; Hunkele, Amanda; Pasternak, Gavril W; Majumdar, Susruta; Hosztafi, Sándor.
Afiliación
  • Urai Á; Department of Pharmaceutical Chemistry, Semmelweis University, Hogyes E. u. 9., Budapest H-1092, Hungary.
  • Váradi A; Molecular Pharmacology and Chemistry Program and Department of Neurology, Memorial Sloan Kettering Cancer Center, 1275 York Ave., New York, NY 10065, USA.
  • Szocs L; Department of Pharmaceutical Chemistry, Semmelweis University, Hogyes E. u. 9., Budapest H-1092, Hungary.
  • Komjáti B; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Szent Gellért tér 4, Budapest 1111, Hungary.
  • Le Rouzic V; Molecular Pharmacology and Chemistry Program and Department of Neurology, Memorial Sloan Kettering Cancer Center, 1275 York Ave., New York, NY 10065, USA.
  • Hunkele A; Molecular Pharmacology and Chemistry Program and Department of Neurology, Memorial Sloan Kettering Cancer Center, 1275 York Ave., New York, NY 10065, USA.
  • Pasternak GW; Molecular Pharmacology and Chemistry Program and Department of Neurology, Memorial Sloan Kettering Cancer Center, 1275 York Ave., New York, NY 10065, USA.
  • Majumdar S; Molecular Pharmacology and Chemistry Program and Department of Neurology, Memorial Sloan Kettering Cancer Center, 1275 York Ave., New York, NY 10065, USA.
  • Hosztafi S; Department of Pharmaceutical Chemistry, Semmelweis University, Hogyes E. u. 9., Budapest H-1092, Hungary.
Medchemcomm ; 8(1): 152-157, 2017 Jan 01.
Article en En | MEDLINE | ID: mdl-28603600
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2017 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2017 Tipo del documento: Article