Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations.

Champer, Jackson; Reeves, Riona; Oh, Suh Yeon; Liu, Chen; Liu, Jingxian; Clark, Andrew G; Messer, Philipp W

Champer, Jackson; Reeves, Riona; Oh, Suh Yeon; Liu, Chen; Liu, Jingxian; Clark, Andrew G; Messer, Philipp W.

Afiliación

Champer J; Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY, United States of America.
Reeves R; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, United States of America.
Oh SY; Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY, United States of America.
Liu C; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, United States of America.
Liu J; Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY, United States of America.
Clark AG; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, United States of America.
Messer PW; Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY, United States of America.

PLoS Genet ; 13(7): e1006796, 2017 07.

Article en En | MEDLINE | ID: mdl-28727785

Asunto(s)

Sistemas CRISPR-Cas/genética; Resistencia a la Enfermedad/genética; Desarrollo Embrionario/genética; Genética de Población; Alelos; Animales; Animales Modificados Genéticamente; Drosophila melanogaster/genética; Fertilización/genética; Conversión Génica/genética; Células Germinativas; Mutación/genética; Transgenes/genética

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Desarrollo Embrionario / Resistencia a la Enfermedad / Sistemas CRISPR-Cas / Genética de Población Límite: Animals Idioma: En Año: 2017 Tipo del documento: Article

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