The UL8 subunit of the helicase-primase complex of herpes simplex virus promotes DNA annealing and has a high affinity for replication forks.

Bermek, Oya; Weller, Sandra K; Griffith, Jack D

Bermek, Oya; Weller, Sandra K; Griffith, Jack D.

Afiliación

Bermek O; From the Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7295 and oya_bermek@med.unc.edu.
Weller SK; Department of Molecular Biology and Biophysics and the Molecular Biology and Biochemistry Graduate Program, University of Connecticut Health Center, Farmington, Connecticut 06030.
Griffith JD; From the Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7295 and.

J Biol Chem ; 292(38): 15611-15621, 2017 09 22.

Article en En | MEDLINE | ID: mdl-28743747

Asunto(s)

ADN Helicasas/metabolismo; ADN Primasa/metabolismo; Replicación del ADN; Herpesvirus Humano 1/enzimología; Herpesvirus Humano 1/genética; Proteínas Virales/metabolismo; Secuencia de Bases; ADN de Cadena Simple/biosíntesis; ADN de Cadena Simple/química; ADN de Cadena Simple/metabolismo; Herpesvirus Humano 1/ultraestructura; Peso Molecular

Palabras clave

DNA annealing; DNA binding protein; DNA replication; UL8; electron microscopy (EM); herpesvirus; protein structure; replication fork

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Virales / Herpesvirus Humano 1 / ADN Helicasas / ADN Primasa / Replicación del ADN Idioma: En Año: 2017 Tipo del documento: Article

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