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Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence.
Aarts, Marieke; Georgilis, Athena; Beniazza, Meryam; Beolchi, Patrizia; Banito, Ana; Carroll, Thomas; Kulisic, Marizela; Kaemena, Daniel F; Dharmalingam, Gopuraja; Martin, Nadine; Reik, Wolf; Zuber, Johannes; Kaji, Keisuke; Chandra, Tamir; Gil, Jesús.
Afiliación
  • Aarts M; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.
  • Georgilis A; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom.
  • Beniazza M; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.
  • Beolchi P; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom.
  • Banito A; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, United Kingdom.
  • Carroll T; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.
  • Kulisic M; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom.
  • Kaemena DF; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.
  • Dharmalingam G; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom.
  • Martin N; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.
  • Reik W; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom.
  • Zuber J; WaferGen Biosystems, L-1526 Luxembourg, Luxembourg.
  • Kaji K; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, United Kingdom.
  • Chandra T; Medical Research Council (MRC) London Institute of Medical Sciences (LMS), London W12 0NN, United Kingdom.
  • Gil J; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London W12 0NN, United Kingdom.
Genes Dev ; 31(20): 2085-2098, 2017 10 15.
Article en En | MEDLINE | ID: mdl-29138277
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Senescencia Celular / Análisis de Secuencia de ARN / Perfilación de la Expresión Génica / ARN Interferente Pequeño / Reprogramación Celular / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Senescencia Celular / Análisis de Secuencia de ARN / Perfilación de la Expresión Génica / ARN Interferente Pequeño / Reprogramación Celular / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article