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Chromosomal instability drives metastasis through a cytosolic DNA response.
Bakhoum, Samuel F; Ngo, Bryan; Laughney, Ashley M; Cavallo, Julie-Ann; Murphy, Charles J; Ly, Peter; Shah, Pragya; Sriram, Roshan K; Watkins, Thomas B K; Taunk, Neil K; Duran, Mercedes; Pauli, Chantal; Shaw, Christine; Chadalavada, Kalyani; Rajasekhar, Vinagolu K; Genovese, Giulio; Venkatesan, Subramanian; Birkbak, Nicolai J; McGranahan, Nicholas; Lundquist, Mark; LaPlant, Quincey; Healey, John H; Elemento, Olivier; Chung, Christine H; Lee, Nancy Y; Imielenski, Marcin; Nanjangud, Gouri; Pe'er, Dana; Cleveland, Don W; Powell, Simon N; Lammerding, Jan; Swanton, Charles; Cantley, Lewis C.
Afiliación
  • Bakhoum SF; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Ngo B; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York 10065, USA.
  • Laughney AM; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York 10065, USA.
  • Cavallo JA; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Murphy CJ; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Ly P; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York 10065, USA.
  • Shah P; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York 10065, USA.
  • Sriram RK; Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, California 92093, USA.
  • Watkins TBK; Nancy E. and Peter C. Meinig School of Biomedical Engineering & Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York 14850, USA.
  • Taunk NK; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York 10065, USA.
  • Duran M; The Francis Crick Institute, London NW1 1AT, UK.
  • Pauli C; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Shaw C; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Chadalavada K; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York 10065, USA.
  • Rajasekhar VK; Institute for Pathology and Molecular Pathology, University Hospital Zurich, Zurich 8091, Switzerland.
  • Genovese G; Molecular Cytogenetics Core, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Venkatesan S; Molecular Cytogenetics Core, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Birkbak NJ; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • McGranahan N; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.
  • Lundquist M; UCL Cancer Institute, London WC1E 6BT, UK.
  • LaPlant Q; The Francis Crick Institute, London NW1 1AT, UK.
  • Healey JH; UCL Cancer Institute, London WC1E 6BT, UK.
  • Elemento O; The Francis Crick Institute, London NW1 1AT, UK.
  • Chung CH; UCL Cancer Institute, London WC1E 6BT, UK.
  • Lee NY; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York 10065, USA.
  • Imielenski M; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Nanjangud G; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Pe'er D; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York 10065, USA.
  • Cleveland DW; Moffitt Cancer Center, Tampa, Florida 33612, USA.
  • Powell SN; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Lammerding J; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York 10065, USA.
  • Swanton C; Molecular Cytogenetics Core, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Cantley LC; Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
Nature ; 553(7689): 467-472, 2018 01 25.
Article en En | MEDLINE | ID: mdl-29342134
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ADN de Neoplasias / Citosol / Inestabilidad Cromosómica / Metástasis de la Neoplasia Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ADN de Neoplasias / Citosol / Inestabilidad Cromosómica / Metástasis de la Neoplasia Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2018 Tipo del documento: Article