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Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.
Badders, Nisha M; Korff, Ane; Miranda, Helen C; Vuppala, Pradeep K; Smith, Rebecca B; Winborn, Brett J; Quemin, Emmanuelle R; Sopher, Bryce L; Dearman, Jennifer; Messing, James; Kim, Nam Chul; Moore, Jennifer; Freibaum, Brian D; Kanagaraj, Anderson P; Fan, Baochang; Tillman, Heather; Chen, Ping-Chung; Wang, Yingzhe; Freeman, Burgess B; Li, Yimei; Kim, Hong Joo; La Spada, Albert R; Taylor, J Paul.
Afiliación
  • Badders NM; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Korff A; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Miranda HC; Howard Hughes Medical Institute, Chevy Chase, Maryland, USA.
  • Vuppala PK; Department of Pediatrics, University of California at San Diego, La Jolla, California, USA.
  • Smith RB; Preclinical Pharmacokinetic Shared Resource, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Winborn BJ; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Quemin ER; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Sopher BL; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Dearman J; Department of Neurology, University of Washington, Seattle, Washington, USA.
  • Messing J; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Kim NC; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Moore J; Howard Hughes Medical Institute, Chevy Chase, Maryland, USA.
  • Freibaum BD; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Kanagaraj AP; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Fan B; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Tillman H; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Chen PC; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Wang Y; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Freeman BB; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Li Y; Preclinical Pharmacokinetic Shared Resource, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Kim HJ; Preclinical Pharmacokinetic Shared Resource, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • La Spada AR; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Taylor JP; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Nat Med ; 24(4): 427-437, 2018 05.
Article en En | MEDLINE | ID: mdl-29505030
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Atrofia Muscular Espinal / Receptores Androgénicos / Degeneración Nerviosa Límite: Animals / Humans / Male Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Atrofia Muscular Espinal / Receptores Androgénicos / Degeneración Nerviosa Límite: Animals / Humans / Male Idioma: En Año: 2018 Tipo del documento: Article