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Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer history.
Engel, Christoph; Rhiem, Kerstin; Hahnen, Eric; Loibl, Sibylle; Weber, Karsten E; Seiler, Sabine; Zachariae, Silke; Hauke, Jan; Wappenschmidt, Barbara; Waha, Anke; Blümcke, Britta; Kiechle, Marion; Meindl, Alfons; Niederacher, Dieter; Bartram, Claus R; Speiser, Dorothee; Schlegelberger, Brigitte; Arnold, Norbert; Wieacker, Peter; Leinert, Elena; Gehrig, Andrea; Briest, Susanne; Kast, Karin; Riess, Olaf; Emons, Günter; Weber, Bernhard H F; Engel, Jutta; Schmutzler, Rita K.
Afiliación
  • Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
  • Rhiem K; Center for Hereditary Breast and Ovarian Cancer and Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Strasse 34, 50931, Cologne, Germany.
  • Hahnen E; Center for Hereditary Breast and Ovarian Cancer and Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Strasse 34, 50931, Cologne, Germany.
  • Loibl S; German Breast Group, Neu-Isenburg, Germany.
  • Weber KE; Centre for Haematology and Oncology Bethanien, Frankfurt, Germany.
  • Seiler S; German Breast Group, Neu-Isenburg, Germany.
  • Zachariae S; German Breast Group, Neu-Isenburg, Germany.
  • Hauke J; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
  • Wappenschmidt B; Center for Hereditary Breast and Ovarian Cancer and Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Strasse 34, 50931, Cologne, Germany.
  • Waha A; Center for Hereditary Breast and Ovarian Cancer and Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Strasse 34, 50931, Cologne, Germany.
  • Blümcke B; Center for Hereditary Breast and Ovarian Cancer and Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Strasse 34, 50931, Cologne, Germany.
  • Kiechle M; Center for Hereditary Breast and Ovarian Cancer and Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Kerpener Strasse 34, 50931, Cologne, Germany.
  • Meindl A; Department of Gynecology and Center for Hereditary Breast and Ovarian Cancer, Klinikum rechts der Isar, Technical University Munich (TUM), Munich, Germany.
  • Niederacher D; Department of Gynecology and Center for Hereditary Breast and Ovarian Cancer, Klinikum rechts der Isar, Technical University Munich (TUM), Munich, Germany.
  • Bartram CR; Department of Gynecology and Obstetrics, University Hospital of the Heinrich-Heine University, Düsseldorf, Germany.
  • Speiser D; Institute of Human Genetics, University Hospital, University of Heidelberg, Heidelberg, Germany.
  • Schlegelberger B; Zentrum für Familiären Brust- und Eierstockkrebs, Klinik für Gynäkologie mit Brustzentrum, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Arnold N; Department of Human Genetics, Hannover Medical School, Hannover, Germany.
  • Wieacker P; Institute of Clinical Molecular Biology/Department of Gynecology and Obstetrics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany.
  • Leinert E; Institute of Human Genetics, University Hospital Münster, Münster, Germany.
  • Gehrig A; Department of Gynecology and Obstetrics, University Hospital Ulm, Ulm, Germany.
  • Briest S; Institute of Human Genetics, University Würzburg, Würzburg, Germany.
  • Kast K; Center for Hereditary Breast and Ovarian Cancer, University Hospital Leipzig, Leipzig, Germany.
  • Riess O; Department of Gynecology and Obstetrics, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Emons G; National Center for Tumor Diseases (NCT), Partner Site Dresden, Dresden, Germany.
  • Weber BHF; German Cancer Consortium (DKTK), Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Engel J; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.
  • Schmutzler RK; Klinik für Gynäkologie und Geburtshilfe, Universitätsmedizin, Göttingen, Germany.
BMC Cancer ; 18(1): 265, 2018 03 07.
Article en En | MEDLINE | ID: mdl-29514593
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Biomarcadores de Tumor / Pruebas Genéticas / Mutación de Línea Germinal / Proteína BRCA1 / Proteína BRCA2 / Neoplasias de la Mama Triple Negativas / Neoplasias de Mama Unilaterales Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Middle aged País/Región como asunto: Europa Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Biomarcadores de Tumor / Pruebas Genéticas / Mutación de Línea Germinal / Proteína BRCA1 / Proteína BRCA2 / Neoplasias de la Mama Triple Negativas / Neoplasias de Mama Unilaterales Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Middle aged País/Región como asunto: Europa Idioma: En Año: 2018 Tipo del documento: Article