MGMT promoter methylation in patients with glioblastoma: is methylation-sensitive high-resolution melting superior to methylation-sensitive polymerase chain reaction assay?
J Neurosurg
; 130(3): 780-788, 2018 05 04.
Article
en En
| MEDLINE
| ID: mdl-29726772
Palabras clave
AUC = area under the curve; GBM = glioblastoma; KPS = Karnofsky Performance Status; MGMT; MGMT = O6-methylguanine-DNA methyltransferase; MS-HRM = methylation-sensitive high-resolution melting; MS-PCR = methylation-sensitive polymerase chain reaction; O6-methylguanine-DNA methyltransferase; OS = overall survival; PFS = progression-free survival; ROC = receiver operating characteristic; TMZ = temozolomide; glioblastoma; methylation-sensitive high-resolution melting; methylation-sensitive polymerase chain reaction; oncology; temozolomide
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Encefálicas
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Metilasas de Modificación del ADN
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Reacción en Cadena de la Polimerasa
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Glioblastoma
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Metilación de ADN
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Proteínas Supresoras de Tumor
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Enzimas Reparadoras del ADN
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Desnaturalización de Ácido Nucleico
Tipo de estudio:
Diagnostic_studies
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Guideline
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Prognostic_studies
Límite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2018
Tipo del documento:
Article