MLKL mediates apoptosis via a mutual regulation with PERK/eIF2&#945; pathway in response to reactive oxygen species generation.

Cao, Wen-Xiang; Li, Ting; Tang, Zheng-Hai; Zhang, Le-Le; Wang, Zhao-Yu; Guo, Xia; Su, Min-Xia; Chen, Xiuping; Lu, Jin-Jian

MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation.

Cao, Wen-Xiang; Li, Ting; Tang, Zheng-Hai; Zhang, Le-Le; Wang, Zhao-Yu; Guo, Xia; Su, Min-Xia; Chen, Xiuping; Lu, Jin-Jian.

Afiliación

Cao WX; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 7014, N22, Avenida da Universidade, Taipa, Macao, China.
Li T; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 7014, N22, Avenida da Universidade, Taipa, Macao, China.
Tang ZH; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 7014, N22, Avenida da Universidade, Taipa, Macao, China.
Zhang LL; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 7014, N22, Avenida da Universidade, Taipa, Macao, China.
Wang ZY; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 7014, N22, Avenida da Universidade, Taipa, Macao, China.
Guo X; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 7014, N22, Avenida da Universidade, Taipa, Macao, China.
Su MX; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 7014, N22, Avenida da Universidade, Taipa, Macao, China.
Chen X; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 7014, N22, Avenida da Universidade, Taipa, Macao, China.
Lu JJ; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 7014, N22, Avenida da Universidade, Taipa, Macao, China. jinjianlu@umac.mo.

Apoptosis ; 23(9-10): 521-531, 2018 10.

Article en En | MEDLINE | ID: mdl-30084053

Asunto(s)

Apoptosis/genética; Factor 2 Eucariótico de Iniciación/genética; Necrosis/genética; Proteínas Quinasas/genética; eIF-2 Quinasa/genética; Apoptosis/efectos de los fármacos; Benzofenantridinas/farmacología; Núcleo Celular/genética; Retículo Endoplásmico/genética; Silenciador del Gen; Humanos; Necrosis/patología; Especies Reactivas de Oxígeno/metabolismo

Palabras clave

Apoptosis; Chelerythrine; MLKL; ROS; eIF2α

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Quinasas / Factor 2 Eucariótico de Iniciación / Apoptosis / EIF-2 Quinasa / Necrosis Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article

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