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Homology modeling and structure-based design improve hydrophobic interaction chromatography behavior of integrin binding antibodies.
Jetha, Arif; Thorsteinson, Nels; Jmeian, Yazen; Jeganathan, Ajitha; Giblin, Patricia; Fransson, Johan.
Afiliación
  • Jetha A; a Department of Antibody Discovery and Development, Northern Biologics Inc ., Toronto , Ontario , Canada.
  • Thorsteinson N; b Department of Scientific Services, Chemical Computing Group ULC , Montreal , Quebec , Canada.
  • Jmeian Y; a Department of Antibody Discovery and Development, Northern Biologics Inc ., Toronto , Ontario , Canada.
  • Jeganathan A; a Department of Antibody Discovery and Development, Northern Biologics Inc ., Toronto , Ontario , Canada.
  • Giblin P; a Department of Antibody Discovery and Development, Northern Biologics Inc ., Toronto , Ontario , Canada.
  • Fransson J; a Department of Antibody Discovery and Development, Northern Biologics Inc ., Toronto , Ontario , Canada.
MAbs ; 10(6): 890-900, 2018.
Article en En | MEDLINE | ID: mdl-30110240
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Modelos Moleculares / Integrinas / Cromatografía Líquida de Alta Presión / Dominios Proteicos / Anticuerpos Monoclonales Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Modelos Moleculares / Integrinas / Cromatografía Líquida de Alta Presión / Dominios Proteicos / Anticuerpos Monoclonales Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article