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piRBase: a comprehensive database of piRNA sequences.
Wang, Jiajia; Zhang, Peng; Lu, Yiping; Li, Yanyan; Zheng, Yu; Kan, Yunchao; Chen, Runsheng; He, Shunmin.
Afiliación
  • Wang J; Key Laboratory of RNA Biology, Center for Big Data Research in Health, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Zhang P; Key Laboratory of RNA Biology, Center for Big Data Research in Health, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Lu Y; School of Life Sciences, Zhengzhou University, Zhengzhou 450001,China.
  • Li Y; Key Laboratory of RNA Biology, Center for Big Data Research in Health, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Zheng Y; University of Chinese Academy of Science, Beijing 100049, China.
  • Kan Y; Key Laboratory of RNA Biology, Center for Big Data Research in Health, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
  • Chen R; University of Chinese Academy of Science, Beijing 100049, China.
  • He S; China-UK-NYNU-RRes Joint Laboratory of insect biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, Nanyang, Henan 473061,China.
Nucleic Acids Res ; 47(D1): D175-D180, 2019 01 08.
Article en En | MEDLINE | ID: mdl-30371818
PIWI-interacting RNAs are a class of small RNAs that is most abundantly expressed in animal germline. Substantial research is going on to reveal the functions of piRNAs in the epigenetic and post-transcriptional regulation of transposons and genes. To collect and annotate these data, we developed piRBase, a database assisting piRNA functional study. Since its launch in 2014, piRBase has integrated 264 data sets from 21 organisms, and the number of collected piRNAs has reached 173 million. The latest piRBase release (v2.0, 2018) was more focused on the comprehensive annotation of piRNA sequences, as well as the increasing number of piRNAs. In addition, piRBase release v2.0 also contained the potential information of piRNA targets and disease related piRNA. All datasets in piRBase is free to access, and available for browse, search and bulk downloads at http://www.regulatoryrna.org/database/piRNA/.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Secuencia de Bases / Biología Computacional / Genómica / Bases de Datos Genéticas / ARN Interferente Pequeño Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Secuencia de Bases / Biología Computacional / Genómica / Bases de Datos Genéticas / ARN Interferente Pequeño Idioma: En Año: 2019 Tipo del documento: Article