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Reduction of microglial progranulin does not exacerbate pathology or behavioral deficits in neuronal progranulin-insufficient mice.
Arrant, Andrew E; Filiano, Anthony J; Patel, Aashka R; Hoffmann, Madelyn Q; Boyle, Nicholas R; Kashyap, Shreya N; Onyilo, Vincent C; Young, Allen H; Roberson, Erik D.
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  • Arrant AE; Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, Alzheimer's Disease Center, Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, United States.
  • Filiano AJ; Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, Alzheimer's Disease Center, Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, United States.
  • Patel AR; Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, Alzheimer's Disease Center, Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, United States.
  • Hoffmann MQ; Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, Alzheimer's Disease Center, Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, United States.
  • Boyle NR; Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, Alzheimer's Disease Center, Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, United States.
  • Kashyap SN; Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, Alzheimer's Disease Center, Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, United States.
  • Onyilo VC; Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, Alzheimer's Disease Center, Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, United States.
  • Young AH; Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, Alzheimer's Disease Center, Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, United States.
  • Roberson ED; Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, Alzheimer's Disease Center, Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, United States. Electronic address: eroberson@uabmc.edu.
Neurobiol Dis ; 124: 152-162, 2019 04.
Article en En | MEDLINE | ID: mdl-30448285
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Encéfalo / Microglía / Progranulinas / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Encéfalo / Microglía / Progranulinas / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article