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Mannan-binding lectin attenuates acetaminophen-induced hepatotoxicity by regulating CYP2E1 expression via ROS-dependent JNK/SP1 pathway.
Li, Huifang; Liu, Yan; Li, Junru; Liu, Yunzhi; Dong, Lijun; Yin, Yue; Yu, Yu; Zhou, Jia; Zhang, Liyun; Lu, Xiao; Chen, Zhengliang; Zuo, Daming.
Afiliación
  • Li H; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
  • Liu Y; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
  • Li J; Department of Pathology, Anhui Chest Hospital, Hefei, China.
  • Liu Y; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
  • Dong L; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
  • Yin Y; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
  • Yu Y; Department of Rheumatology and Immunology, Puyang People's Hospital, Puyang, China.
  • Zhou J; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
  • Zhang L; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
  • Lu X; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
  • Chen Z; Institute of Molecular Immunology, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China.
  • Zuo D; Department of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Eur J Immunol ; 49(4): 564-575, 2019 04.
Article en En | MEDLINE | ID: mdl-30706943
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Factor de Transcripción Sp1 / Especies Reactivas de Oxígeno / Citocromo P-450 CYP2E1 / Lectina de Unión a Manosa / Proteínas Quinasas JNK Activadas por Mitógenos / Enfermedad Hepática Inducida por Sustancias y Drogas / Acetaminofén Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Factor de Transcripción Sp1 / Especies Reactivas de Oxígeno / Citocromo P-450 CYP2E1 / Lectina de Unión a Manosa / Proteínas Quinasas JNK Activadas por Mitógenos / Enfermedad Hepática Inducida por Sustancias y Drogas / Acetaminofén Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article