Identification and clinical validation of a multigene assay that interrogates the biology of cancer stem cells and predicts metastasis in breast cancer: A retrospective consecutive study.

Pece, Salvatore; Disalvatore, Davide; Tosoni, Daniela; Vecchi, Manuela; Confalonieri, Stefano; Bertalot, Giovanni; Viale, Giuseppe; Colleoni, Marco; Veronesi, Paolo; Galimberti, Viviana; Di Fiore, Pier Paolo

Pece, Salvatore; Disalvatore, Davide; Tosoni, Daniela; Vecchi, Manuela; Confalonieri, Stefano; Bertalot, Giovanni; Viale, Giuseppe; Colleoni, Marco; Veronesi, Paolo; Galimberti, Viviana; Di Fiore, Pier Paolo.

Afiliación

Pece S; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, 20142 Milano, Italy. Electronic address: salvatore.pece@ieo.it.
Disalvatore D; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Tosoni D; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Vecchi M; IFOM, The FIRC Institute for Molecular Oncology Foundation, Via Adamello 16, 20139 Milan, Italy.
Confalonieri S; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Bertalot G; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Viale G; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, 20142 Milano, Italy.
Colleoni M; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Veronesi P; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, 20142 Milano, Italy.
Galimberti V; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy.
Di Fiore PP; European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milan, Italy; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, 20142 Milano, Italy. Electronic address: pierpaolo.difiore@ieo.it.

EBioMedicine ; 42: 352-362, 2019 Apr.

Article en En | MEDLINE | ID: mdl-30846393

Asunto(s)

Biomarcadores de Tumor; Neoplasias de la Mama/genética; Neoplasias de la Mama/patología; Familia de Multigenes; Células Madre Neoplásicas/metabolismo; Adulto; Anciano; Neoplasias de la Mama/mortalidad; Femenino; Perfilación de la Expresión Génica; Genómica/métodos; Humanos; Persona de Mediana Edad; Clasificación del Tumor; Metástasis de la Neoplasia; Estadificación de Neoplasias; Pronóstico; Modelos de Riesgos Proporcionales; Estudios Retrospectivos; Transcriptoma

Palabras clave

Biomarkers; Breast cancer; Cancer stem cells; Metastasis; Prognostic signatures

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias de la Mama / Biomarcadores de Tumor / Familia de Multigenes Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Middle aged Idioma: En Año: 2019 Tipo del documento: Article

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