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DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo.
Thompson, Karen J; Khajehali, Elham; Bradley, Sophie J; Navarrete, Jovana S; Huang, Xi Ping; Slocum, Samuel; Jin, Jian; Liu, Jing; Xiong, Yan; Olsen, Reid H J; Diberto, Jeffrey F; Boyt, Kristen M; Pina, Melanie M; Pati, Dipanwita; Molloy, Colin; Bundgaard, Christoffer; Sexton, Patrick M; Kash, Thomas L; Krashes, Michael J; Christopoulos, Arthur; Roth, Bryan L; Tobin, Andrew B.
Afiliación
  • Thompson KJ; Centre for Translational Pharmacology, Institute of Molecular, Cell, and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland G12 8QQ, United Kingdom.
  • Khajehali E; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
  • Bradley SJ; Centre for Translational Pharmacology, Institute of Molecular, Cell, and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland G12 8QQ, United Kingdom.
  • Navarrete JS; Diabetes, Endocrinology, and Obesity Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States.
  • Huang XP; National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21224, United States.
  • Slocum S; Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina NC2751, United States.
  • Jin J; Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina NC2751, United States.
  • Liu J; Center for Chemical Biology and Drug Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY10029, United States.
  • Xiong Y; Center for Chemical Biology and Drug Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY10029, United States.
  • Olsen RHJ; Center for Chemical Biology and Drug Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY10029, United States.
  • Diberto JF; Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina NC2751, United States.
  • Boyt KM; Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina NC2751, United States.
  • Pina MM; Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina NC2751, United States.
  • Pati D; Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina NC2751, United States.
  • Molloy C; Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina NC2751, United States.
  • Bundgaard C; Centre for Translational Pharmacology, Institute of Molecular, Cell, and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland G12 8QQ, United Kingdom.
  • Sexton PM; Neuroscience, Eli Lilly & Co., Erl Wood Manor, Windlesham, Surrey GU20 6PH, United Kingdom.
  • Kash TL; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
  • Krashes MJ; Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina NC2751, United States.
  • Christopoulos A; Diabetes, Endocrinology, and Obesity Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States.
  • Roth BL; National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21224, United States.
  • Tobin AB; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
ACS Pharmacol Transl Sci ; 1(1): 61-72, 2018 Sep 14.
Article en En | MEDLINE | ID: mdl-30868140
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2018 Tipo del documento: Article