PE_PGRS62 promotes the survival of Mycobacterium smegmatis within macrophages via disrupting ER stress-mediated apoptosis.

Long, Quanxin; Xiang, Xiaohong; Yin, Qingqin; Li, Shuangjiang; Yang, Wenmin; Sun, Hang; Liu, Qi; Xie, Jianping; Deng, Wanyan

Long, Quanxin; Xiang, Xiaohong; Yin, Qingqin; Li, Shuangjiang; Yang, Wenmin; Sun, Hang; Liu, Qi; Xie, Jianping; Deng, Wanyan.

Afiliación

Long Q; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Xiang X; School of Pharmacy, Chongqing Medical and Pharmaceutical College, Chongqing, People's Republic of China.
Yin Q; Department of Respiratory Medicine, China National Clinical Research Center for Respiratory Diseases, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, People's Republic of China.
Li S; Department of Physical Examination Center, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Yang W; State Key Laboratory Breeding Base of Eco-Environment and Bio-Resource of the Three Gorges Area, Key Laboratory of Eco-environments in Three Gorges Reservoir Region, Ministry of Education, School of Life Sciences, Institute of Modern Biopharmaceuticals, Southwest University, People's Republic of Chi
Sun H; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Liu Q; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.
Xie J; State Key Laboratory Breeding Base of Eco-Environment and Bio-Resource of the Three Gorges Area, Key Laboratory of Eco-environments in Three Gorges Reservoir Region, Ministry of Education, School of Life Sciences, Institute of Modern Biopharmaceuticals, Southwest University, People's Republic of Chi
Deng W; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China.

J Cell Physiol ; 234(11): 19774-19784, 2019 11.

Article en En | MEDLINE | ID: mdl-30937925

Asunto(s)

Proteínas Bacterianas/genética; Mycobacterium smegmatis/genética; Mycobacterium tuberculosis/genética; Tuberculosis/genética; Apoptosis/genética; Proteínas Bacterianas/metabolismo; Estrés del Retículo Endoplásmico/genética; Regulación Bacteriana de la Expresión Génica/genética; Humanos; Macrófagos/microbiología; Mycobacterium smegmatis/patogenicidad; Mycobacterium tuberculosis/patogenicidad; Fagosomas/genética; Tuberculosis/microbiología

Palabras clave

ER stress response; Mycobacterium tuberculosis; PE_PGRS62; apoptosis; macrophage; tuberculosis

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Tuberculosis / Mycobacterium smegmatis / Mycobacterium tuberculosis Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article

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