Interaction of bovine erythrocyte N-glycolylneuraminic acid-containing gangliosides and glycoproteins with a human Hanganutziu-Deicher serum.
Mol Immunol
; 23(7): 693-700, 1986 Jul.
Article
en En
| MEDLINE
| ID: mdl-3099177
ABSTRACT
A human Hanganutziu-Deicher (H-D) serum reacted with N-glycolylneuraminic acid (NeuGc)-containing gangliosides and glycoproteins isolated from bovine erythrocyte membranes. Three populations of H-D antibodies were identified in the human H-D serum. One population very likely recognized the NeuGc-Gal sequence; a second population appears to recognize additional sugars in the oligosaccharide sequence, e.g. NeuGc-Gal-GlcNAc; while a third population may also recognize polypeptide determinants in addition to the NeuGc-Gal-GlcNAc sequence. The H-D serum distinguished two high mol. wt glycoproteins (HMGP I and II) present in crude extracts of bovine erythrocyte membranes. These glycoproteins were separated by repetitive fractionation on Sephacryl S-1000 in the presence of urea and their composition determined.
Buscar en Google
Banco de datos:
MEDLINE
Asunto principal:
Anticuerpos Heterófilos
/
Glicoproteínas
/
Membrana Eritrocítica
/
Gangliósidos
/
Ácidos Neuramínicos
Límite:
Animals
/
Humans
Idioma:
En
Año:
1986
Tipo del documento:
Article