Synthesis of <sup>18</sup>F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [<sup>18</sup>F]fluoride.

Synthesis of ¹⁸F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [¹⁸F]fluoride.

Sap, Jeroen B I; Wilson, Thomas C; Kee, Choon Wee; Straathof, Natan J W; Ende, Christopher W Am; Mukherjee, Paramita; Zhang, Lei; Genicot, Christophe; Gouverneur, Véronique.

Afiliación

Sap JBI; Chemistry Research Laboratory , Department of Chemistry , Oxford University , OX1 3TA Oxford , UK . Email: veronique.gouverneur@chem.ox.ac.uk ; Tel: +44 (0)1865 285002.
Wilson TC; Chemistry Research Laboratory , Department of Chemistry , Oxford University , OX1 3TA Oxford , UK . Email: veronique.gouverneur@chem.ox.ac.uk ; Tel: +44 (0)1865 285002.
Kee CW; Chemistry Research Laboratory , Department of Chemistry , Oxford University , OX1 3TA Oxford , UK . Email: veronique.gouverneur@chem.ox.ac.uk ; Tel: +44 (0)1865 285002.
Straathof NJW; Chemistry Research Laboratory , Department of Chemistry , Oxford University , OX1 3TA Oxford , UK . Email: veronique.gouverneur@chem.ox.ac.uk ; Tel: +44 (0)1865 285002.
Ende CWA; Pfizer Inc., Medicine Design , Eastern Point Road, Groton, Connecticut 06340, and 1 Portland Street , Cambridge , Massachusetts 02139 , USA.
Mukherjee P; Pfizer Inc., Medicine Design , Eastern Point Road, Groton, Connecticut 06340, and 1 Portland Street , Cambridge , Massachusetts 02139 , USA.
Zhang L; Pfizer Inc., Medicine Design , Eastern Point Road, Groton, Connecticut 06340, and 1 Portland Street , Cambridge , Massachusetts 02139 , USA.
Genicot C; Global Chemistry, UCB New Medicines , UCB Biopharma Sprl , 1420 Braine-L'Alleud , Belgium.
Gouverneur V; Chemistry Research Laboratory , Department of Chemistry , Oxford University , OX1 3TA Oxford , UK . Email: veronique.gouverneur@chem.ox.ac.uk ; Tel: +44 (0)1865 285002.

Chem Sci ; 10(11): 3237-3241, 2019 Mar 21.

Article en En | MEDLINE | ID: mdl-30996907

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2019 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2019 Tipo del documento: Article