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Histone H3K27 dimethyl loss is highly specific for malignant peripheral nerve sheath tumor and distinguishes true PRC2 loss from isolated H3K27 trimethyl loss.
Marchione, Dylan M; Lisby, Amanda; Viaene, Angela N; Santi, Mariarita; Nasrallah, MacLean; Wang, Li-Ping; Williams, Erik A; Larque, Ana B; Chebib, Ivan; Garcia, Benjamin A; Wojcik, John B.
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  • Marchione DM; Department of Biochemistry and Biophysics, and Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Lisby A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Viaene AN; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Santi M; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Nasrallah M; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Wang LP; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Williams EA; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Larque AB; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
  • Chebib I; Department of Pathology, Hospital Clinic of Barcelona, Barcelona, Spain.
  • Garcia BA; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
  • Wojcik JB; Department of Biochemistry and Biophysics, and Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Mod Pathol ; 32(10): 1434-1446, 2019 10.
Article en En | MEDLINE | ID: mdl-31175328
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Histonas / Biomarcadores de Tumor / Neurofibrosarcoma / Metilación de ADN / Complejo Represivo Polycomb 2 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Histonas / Biomarcadores de Tumor / Neurofibrosarcoma / Metilación de ADN / Complejo Represivo Polycomb 2 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article