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First-Time-in-Human Study and Prediction of Early Bactericidal Activity for GSK3036656, a Potent Leucyl-tRNA Synthetase Inhibitor for Tuberculosis Treatment.
Tenero, David; Derimanov, Geo; Carlton, Alex; Tonkyn, John; Davies, Matt; Cozens, Simon; Gresham, Stephanie; Gaudion, Alison; Puri, Adeep; Muliaditan, Morris; Rullas-Trincado, Joaquin; Mendoza-Losana, Alfonso; Skingsley, Andrew; Barros-Aguirre, David.
Afiliación
  • Tenero D; GlaxoSmithKline Clinical Pharmacology Modeling and Simulation, Collegeville, Pennsylvania, USA.
  • Derimanov G; GlaxoSmithKline Clinical Pharmacology and Experimental Medicine, Collegeville, Pennsylvania, USA.
  • Carlton A; GlaxoSmithKline Biostatistics, Stockley Park, London, United Kingdom.
  • Tonkyn J; GlaxoSmithKline Global Sciences and Delivery, Stevenage, Hertfordshire, United Kingdom.
  • Davies M; GlaxoSmithKline Safety and Medical Governance, Stockley Park, London, United Kingdom.
  • Cozens S; GlaxoSmithKline, Translation Project Specialist Team, Ware, Hertfordshire, United Kingdom.
  • Gresham S; GlaxoSmithKline, Mechanistic Safety and Disposition, Ware, Hertfordshire, United Kingdom.
  • Gaudion A; Hammersmith Medicines Research, London, United Kingdom.
  • Puri A; Hammersmith Medicines Research, London, United Kingdom.
  • Muliaditan M; GlaxoSmithKline DMPK Modelling, Stevenage, Hertfordshire, United Kingdom.
  • Rullas-Trincado J; GlaxoSmithKline Global Health, TBDPU, Tres Cantos, Madrid, Spain.
  • Mendoza-Losana A; GlaxoSmithKline Global Health, TBDPU, Tres Cantos, Madrid, Spain.
  • Skingsley A; GlaxoSmithKline Global Health Clinical Drug Development, Stockley Park, London, United Kingdom.
  • Barros-Aguirre D; GlaxoSmithKline Global Health, TBDPU, Tres Cantos, Madrid, Spain david.a.barros@gsk.com.
Antimicrob Agents Chemother ; 63(8)2019 08.
Article en En | MEDLINE | ID: mdl-31182528
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tuberculosis / Compuestos de Boro / Compuestos Heterocíclicos con 2 Anillos / Antituberculosos Tipo de estudio: Clinical_trials / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tuberculosis / Compuestos de Boro / Compuestos Heterocíclicos con 2 Anillos / Antituberculosos Tipo de estudio: Clinical_trials / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Año: 2019 Tipo del documento: Article