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Inter-Active Site Communication Mediated by the Dimer Interface ß-Sheet in the Half-the-Sites Enzyme, Thymidylate Synthase.
Sapienza, Paul J; Popov, Konstantin I; Mowrey, David D; Falk, Bradley T; Dokholyan, Nikolay V; Lee, Andrew L.
Afiliación
  • Sapienza PJ; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy , The University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599-7355 , United States.
  • Popov KI; Department of Biochemistry and Biophysics, School of Medicine , The University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
  • Mowrey DD; Department of Biochemistry and Biophysics, School of Medicine , The University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
  • Falk BT; Department of Biochemistry and Biophysics, School of Medicine , The University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
  • Dokholyan NV; Department of Pharmacology and Department of Biochemistry and Molecular Biology , Penn State College of Medicine , Hershey , Pennsylvania 17033 , United States.
  • Lee AL; Department of Chemistry and Department of Biomedical Engineering , The Pennsylvania State University , University Park , Pennsylvania 16801 , United States.
Biochemistry ; 58(30): 3302-3313, 2019 07 30.
Article en En | MEDLINE | ID: mdl-31283187

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Timidilato Sintasa / Multimerización de Proteína Idioma: En Año: 2019 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Timidilato Sintasa / Multimerización de Proteína Idioma: En Año: 2019 Tipo del documento: Article