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A fragment-like approach to PYCR1 inhibition.
Milne, Kirsty; Sun, Jianhui; Zaal, Esther A; Mowat, Jenna; Celie, Patrick H N; Fish, Alexander; Berkers, Celia R; Forlani, Giuseppe; Loayza-Puch, Fabricio; Jamieson, Craig; Agami, Reuven.
Afiliación
  • Milne K; Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, Glasgow G1 1XL, United Kingdom.
  • Sun J; H5 Division of Oncogenomics, Oncode Institute, The Netherlands Cancer Institute, 121 Plesmanlaan, 1066 CX Amsterdam, The Netherlands.
  • Zaal EA; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.
  • Mowat J; Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, Glasgow G1 1XL, United Kingdom.
  • Celie PHN; H5 Division of Oncogenomics, Oncode Institute, The Netherlands Cancer Institute, 121 Plesmanlaan, 1066 CX Amsterdam, The Netherlands; NKI Protein Facility, Division of Biochemistry, The Netherlands Cancer Institute, 121 Plesmanlaan, 1066 CX Amsterdam, The Netherlands.
  • Fish A; H5 Division of Oncogenomics, Oncode Institute, The Netherlands Cancer Institute, 121 Plesmanlaan, 1066 CX Amsterdam, The Netherlands; NKI Protein Facility, Division of Biochemistry, The Netherlands Cancer Institute, 121 Plesmanlaan, 1066 CX Amsterdam, The Netherlands.
  • Berkers CR; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 2, 3584 CM Utrecht, The Netherlands.
  • Forlani G; Department of Life Science and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.
  • Loayza-Puch F; H5 Division of Oncogenomics, Oncode Institute, The Netherlands Cancer Institute, 121 Plesmanlaan, 1066 CX Amsterdam, The Netherlands. Electronic address: f.loayza-puch@dkfz-heidelberg.de.
  • Jamieson C; Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, Glasgow G1 1XL, United Kingdom. Electronic address: craig.jamieson@strath.ac.uk.
  • Agami R; H5 Division of Oncogenomics, Oncode Institute, The Netherlands Cancer Institute, 121 Plesmanlaan, 1066 CX Amsterdam, The Netherlands; Department of Molecular Genetics, Erasmus MC, Rotterdam University, The Netherlands. Electronic address: r.agami@nki.nl.
Bioorg Med Chem Lett ; 29(18): 2626-2631, 2019 09 15.
Article en En | MEDLINE | ID: mdl-31362921
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pargilina / Pirrolina Carboxilato Reductasas / Inhibidores Enzimáticos / Bibliotecas de Moléculas Pequeñas / Antineoplásicos Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pargilina / Pirrolina Carboxilato Reductasas / Inhibidores Enzimáticos / Bibliotecas de Moléculas Pequeñas / Antineoplásicos Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article