Characterization and engineering control of the effects of reactive oxygen species on the conversion of sterols to steroid synthons in Mycobacterium neoaurum.

Sun, Wan-Ju; Wang, Li; Liu, Hao-Hao; Liu, Yong-Jun; Ren, Yu-Hong; Wang, Feng-Qing; Wei, Dong-Zhi

Sun, Wan-Ju; Wang, Li; Liu, Hao-Hao; Liu, Yong-Jun; Ren, Yu-Hong; Wang, Feng-Qing; Wei, Dong-Zhi.

Afiliación

Sun WJ; State Key Laboratory of Bioreactor Engineering, Newworld Institute of Biotechnology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
Wang L; State Key Laboratory of Bioreactor Engineering, Newworld Institute of Biotechnology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
Liu HH; State Key Laboratory of Bioreactor Engineering, Newworld Institute of Biotechnology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
Liu YJ; State Key Laboratory of Bioreactor Engineering, Newworld Institute of Biotechnology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
Ren YH; State Key Laboratory of Bioreactor Engineering, Newworld Institute of Biotechnology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
Wang FQ; State Key Laboratory of Bioreactor Engineering, Newworld Institute of Biotechnology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China. Electronic address: fqwang@ecust.edu.cn.
Wei DZ; State Key Laboratory of Bioreactor Engineering, Newworld Institute of Biotechnology, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China. Electronic address: dzhwei@ecust.edu.cn.

Metab Eng ; 56: 97-110, 2019 12.

Article en En | MEDLINE | ID: mdl-31513889

Asunto(s)

Cisteína; Ergotioneína; Glicopéptidos; Inositol; Ingeniería Metabólica; Mycobacteriaceae; Especies Reactivas de Oxígeno/metabolismo; Esteroles/metabolismo; Cisteína/biosíntesis; Cisteína/genética; Ergotioneína/biosíntesis; Ergotioneína/genética; Glicopéptidos/biosíntesis; Glicopéptidos/genética; Inositol/biosíntesis; Inositol/genética; Mycobacteriaceae/genética; Mycobacteriaceae/metabolismo

Palabras clave

Catalase; Ergothioneine; Mycobacteria; Mycothiol; Reactive oxygen species; Sterol catabolism

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Esteroles / Glicopéptidos / Especies Reactivas de Oxígeno / Cisteína / Ergotioneína / Ingeniería Metabólica / Inositol / Mycobacteriaceae Idioma: En Año: 2019 Tipo del documento: Article

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