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Inhibition of Δ24-dehydrocholesterol reductase activates pro-resolving lipid mediator biosynthesis and inflammation resolution.
Körner, Andreas; Zhou, Enchen; Müller, Christoph; Mohammed, Yassene; Herceg, Sandra; Bracher, Franz; Rensen, Patrick C N; Wang, Yanan; Mirakaj, Valbona; Giera, Martin.
Afiliación
  • Körner A; Department of Anesthesiology and Intensive Care Medicine, Molecular Intensive Care Medicine, Eberhard Karls University Tübingen, 72072 Tübingen, Germany.
  • Zhou E; Department of Medicine, Division of Endocrinology, and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.
  • Müller C; Department of Pharmacy-Center for Drug Research, Ludwig Maximilians University Munich, 81377 Munich, Germany.
  • Mohammed Y; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.
  • Herceg S; Department of Pharmacy-Center for Drug Research, Ludwig Maximilians University Munich, 81377 Munich, Germany.
  • Bracher F; Department of Pharmacy-Center for Drug Research, Ludwig Maximilians University Munich, 81377 Munich, Germany.
  • Rensen PCN; Department of Medicine, Division of Endocrinology, and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.
  • Wang Y; Department of Medicine, Division of Endocrinology, and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.
  • Mirakaj V; Department of Anesthesiology and Intensive Care Medicine, Molecular Intensive Care Medicine, Eberhard Karls University Tübingen, 72072 Tübingen, Germany.
  • Giera M; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333ZA Leiden, The Netherlands m.a.giera@lumc.nl.
Proc Natl Acad Sci U S A ; 116(41): 20623-20634, 2019 10 08.
Article en En | MEDLINE | ID: mdl-31548397
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Peritonitis / Regulación de la Expresión Génica / Colesterol / Mediadores de Inflamación / Oxidorreductasas actuantes sobre Donantes de Grupo CH-CH / Lípidos / Antiinflamatorios / Proteínas del Tejido Nervioso Límite: Animals / Female / Humans Idioma: En Año: 2019 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Peritonitis / Regulación de la Expresión Génica / Colesterol / Mediadores de Inflamación / Oxidorreductasas actuantes sobre Donantes de Grupo CH-CH / Lípidos / Antiinflamatorios / Proteínas del Tejido Nervioso Límite: Animals / Female / Humans Idioma: En Año: 2019 Tipo del documento: Article