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A Rare Variant Nonparametric Linkage Method for Nuclear and Extended Pedigrees with Application to Late-Onset Alzheimer Disease via WGS Data.
Zhao, Linhai; He, Zongxiao; Zhang, Di; Wang, Gao T; Renton, Alan E; Vardarajan, Badri N; Nothnagel, Michael; Goate, Alison M; Mayeux, Richard; Leal, Suzanne M.
Afiliación
  • Zhao L; Center for Statistical Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
  • He Z; Center for Statistical Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Zhang D; Center for Statistical Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Wang GT; Department of Human Genetics, The University of Chicago, Chicago, IL 60637, USA.
  • Renton AE; Department of Neuroscience and Ronald M. Loeb Center for Alzheimer Disease, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Vardarajan BN; Department of Neurology, Taub Institute on Alzheimer Disease and the Aging Brain, and Gertrude H. Sergievsky Center, Columbia University, New York, NY 10027, USA.
  • Nothnagel M; Cologne Center for Genomics, Department of Statistical Genetics and Bioinformatics, University of Cologne, 50931 Cologne, Germany; University Hospital Cologne, 50937 Cologne, Germany.
  • Goate AM; Department of Neuroscience and Ronald M. Loeb Center for Alzheimer Disease, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Departments of Genetics and Genomic Sciences and Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA.
  • Mayeux R; Department of Neurology, Taub Institute on Alzheimer Disease and the Aging Brain, and Gertrude H. Sergievsky Center, Columbia University, New York, NY 10027, USA.
  • Leal SM; Center for Statistical Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Department of Neurology, Taub Institute on Alzheimer Disease and the Aging Brain, and Gertrude H. Sergievsky Center, Columbia University, New York, NY 10027, USA; Center for Statistical Genetics, Columbia University
Am J Hum Genet ; 105(4): 822-835, 2019 10 03.
Article en En | MEDLINE | ID: mdl-31585107
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Alzheimer / Secuenciación Completa del Genoma / Ligamiento Genético Límite: Female / Humans / Male Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Alzheimer / Secuenciación Completa del Genoma / Ligamiento Genético Límite: Female / Humans / Male Idioma: En Año: 2019 Tipo del documento: Article