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Integrated drug profiling and CRISPR screening identify essential pathways for CAR T-cell cytotoxicity.
Dufva, Olli; Koski, Jan; Maliniemi, Pilvi; Ianevski, Aleksandr; Klievink, Jay; Leitner, Judith; Pölönen, Petri; Hohtari, Helena; Saeed, Khalid; Hannunen, Tiina; Ellonen, Pekka; Steinberger, Peter; Kankainen, Matti; Aittokallio, Tero; Keränen, Mikko A I; Korhonen, Matti; Mustjoki, Satu.
Afiliación
  • Dufva O; Hematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
  • Koski J; Translational Immunology Research Program and.
  • Maliniemi P; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.
  • Ianevski A; iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland.
  • Klievink J; Finnish Red Cross Blood Service, Helsinki, Finland.
  • Leitner J; Finnish Red Cross Blood Service, Helsinki, Finland.
  • Pölönen P; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
  • Hohtari H; Helsinki Institute for Information Technology, Department of Computer Science, Aalto University, Espoo, Finland.
  • Saeed K; Hematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
  • Hannunen T; Translational Immunology Research Program and.
  • Ellonen P; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.
  • Steinberger P; Centre for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Medical University of Vienna, Vienna, Austria.
  • Kankainen M; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland; and.
  • Aittokallio T; Hematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
  • Keränen MAI; Translational Immunology Research Program and.
  • Korhonen M; Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.
  • Mustjoki S; Hematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
Blood ; 135(9): 597-609, 2020 02 27.
Article en En | MEDLINE | ID: mdl-31830245
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ensayos de Selección de Medicamentos Antitumorales / Linfocitos T Citotóxicos / Inmunoterapia Adoptiva / Resistencia a Antineoplásicos / Citotoxicidad Inmunológica / Leucemia-Linfoma Linfoblástico de Células Precursoras Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ensayos de Selección de Medicamentos Antitumorales / Linfocitos T Citotóxicos / Inmunoterapia Adoptiva / Resistencia a Antineoplásicos / Citotoxicidad Inmunológica / Leucemia-Linfoma Linfoblástico de Células Precursoras Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article