Enhancement of Autophagy and Solubilization of Ataxin-2 Alleviate Apoptosis in Spinocerebellar Ataxia Type 2 Patient Cells.

Wardman, Jonathan Henry; Henriksen, Emil Elbæk; Marthaler, Adele Gabriele; Nielsen, Jørgen Erik; Nielsen, Troels Tolstrup

Wardman, Jonathan Henry; Henriksen, Emil Elbæk; Marthaler, Adele Gabriele; Nielsen, Jørgen Erik; Nielsen, Troels Tolstrup.

Afiliación

Wardman JH; Neurogenetics Clinic & Research Laboratory, Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Henriksen EE; Neurogenetics Clinic & Research Laboratory, Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Marthaler AG; Neurogenetics Clinic & Research Laboratory, Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Nielsen JE; Neurogenetics Clinic & Research Laboratory, Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Nielsen TT; Neurogenetics Clinic & Research Laboratory, Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. troels.tolstrup.nielsen@regionh.dk.

Cerebellum ; 19(2): 165-181, 2020 Apr.

Article en En | MEDLINE | ID: mdl-31898278

Asunto(s)

Apoptosis/fisiología; Ataxina-2/metabolismo; Autofagia/fisiología; Ataxias Espinocerebelosas/metabolismo; Células Cultivadas; Fibroblastos/metabolismo; Humanos; Estrés Oxidativo/fisiología; Ataxias Espinocerebelosas/fisiopatología

Palabras clave

Ataxia; Autophagy; Neurodegenerative disease; Polyglutamine disease

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Autofagia / Apoptosis / Ataxias Espinocerebelosas / Ataxina-2 Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article

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