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Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in EGFR-Mutant Lung Cancer.
Schoenfeld, Adam J; Chan, Joseph M; Kubota, Daisuke; Sato, Hiroki; Rizvi, Hira; Daneshbod, Yahya; Chang, Jason C; Paik, Paul K; Offin, Michael; Arcila, Maria E; Davare, Monika A; Shinde, Ujwal; Pe'er, Dana; Rekhtman, Natasha; Kris, Mark G; Somwar, Romel; Riely, Gregory J; Ladanyi, Marc; Yu, Helena A.
Afiliación
  • Schoenfeld AJ; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
  • Chan JM; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
  • Kubota D; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Sato H; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering, New York, New York.
  • Rizvi H; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
  • Daneshbod Y; Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering, New York, New York.
  • Chang JC; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Paik PK; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Offin M; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
  • Arcila ME; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
  • Davare MA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Shinde U; Department of Pediatrics, Oregon Health & Science University, Portland, Oregon.
  • Pe'er D; Department of Biochemistry, Oregon Health & Science University, Portland, Oregon.
  • Rekhtman N; Program for Computational and System Biology, Sloan Kettering Institute, Memorial Sloan Kettering, New York, New York.
  • Kris MG; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Somwar R; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
  • Riely GJ; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Ladanyi M; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
  • Yu HA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Clin Cancer Res ; 26(11): 2654-2663, 2020 06 01.
Article en En | MEDLINE | ID: mdl-31911548

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article