Hepatocyte Growth Factor Receptor overexpression predicts reduced survival but its targeting is not effective in unselected HNSCC patients.

Khan, Martin; Khaznadar, Sami S; Routila, Johannes; Ventelä, Sami; Schmid, Elke; Gebhart, Bastian; Becker, Eva T; Roider, Helge G; Perala, Merja; Schmitz, Arndt A; Krahn, Thomas; von Ahsen, Oliver

Khan, Martin; Khaznadar, Sami S; Routila, Johannes; Ventelä, Sami; Schmid, Elke; Gebhart, Bastian; Becker, Eva T; Roider, Helge G; Perala, Merja; Schmitz, Arndt A; Krahn, Thomas; von Ahsen, Oliver.

Afiliación

Khan M; Charité, Berlin, Augustenburger Platz 1, Berlin, Germany.
Khaznadar SS; Bayer AG, Research & Development, Pharmaceuticals, Berlin, Germany.
Routila J; Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku, Finland.
Ventelä S; Department for Otorhinolaryngology - Head and Neck Surgery, Turku University Hospital, Turku, Finland.
Schmid E; Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku, Finland.
Gebhart B; Department for Otorhinolaryngology - Head and Neck Surgery, Turku University Hospital, Turku, Finland.
Becker ET; Bayer AG, Research & Development, Pharmaceuticals, Berlin, Germany.
Roider HG; Charité, Berlin, Augustenburger Platz 1, Berlin, Germany.
Perala M; Charité, Berlin, Augustenburger Platz 1, Berlin, Germany.
Schmitz AA; Bayer AG, Research & Development, Pharmaceuticals, Berlin, Germany.
Krahn T; Auria Biobank, Kiinamyllynkatu 8, Turku, Finland.
von Ahsen O; Bayer AG, Research & Development, Pharmaceuticals, Berlin, Germany.

Head Neck ; 42(4): 625-635, 2020 04.

Article en En | MEDLINE | ID: mdl-31919967

Asunto(s)

Carcinoma de Células Escamosas; Neoplasias de Cabeza y Cuello; Carcinoma de Células Escamosas/tratamiento farmacológico; Carcinoma de Células Escamosas/genética; Línea Celular Tumoral; Proliferación Celular; Neoplasias de Cabeza y Cuello/tratamiento farmacológico; Neoplasias de Cabeza y Cuello/genética; Humanos; Proteínas Proto-Oncogénicas c-met/genética; Carcinoma de Células Escamosas de Cabeza y Cuello/tratamiento farmacológico; Carcinoma de Células Escamosas de Cabeza y Cuello/genética

Palabras clave

HNSCC; MET; MSD; immunohistochemistry; tyrosine kinase inhibitor

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Neoplasias de Cabeza y Cuello Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article

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