Exosomal miR-146a-5p from Treponema pallidum-stimulated macrophages reduces endothelial cells permeability and monocyte transendothelial migration by targeting JAM-C.

Hu, Wenlong; Xu, Bufang; Zhang, Jingping; Kou, Caixia; Liu, Jinquan; Wang, Qianqiu; Zhang, Ruili

Hu, Wenlong; Xu, Bufang; Zhang, Jingping; Kou, Caixia; Liu, Jinquan; Wang, Qianqiu; Zhang, Ruili.

Afiliación

Hu W; Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing, Jiangsu Province, China; Department of Dermatology, Xuzhong Medical University Affiliated Hospital of Lianyungang, Lianyungang, Jiangsu, China.
Xu B; Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing, Jiangsu Province, China.
Zhang J; Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing, Jiangsu Province, China.
Kou C; Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing, Jiangsu Province, China.
Liu J; Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing, Jiangsu Province, China.
Wang Q; Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing, Jiangsu Province, China. Electronic address: wangqianqiunj@126.com.
Zhang R; Department of Dermatology, Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China. Electronic address: reallyvictor@126.com.

Exp Cell Res ; 388(1): 111823, 2020 03 01.

Article en En | MEDLINE | ID: mdl-31926946

Asunto(s)

Moléculas de Adhesión Celular/genética; Exosomas/metabolismo; Células Endoteliales de la Vena Umbilical Humana/metabolismo; Macrófagos/metabolismo; MicroARNs/genética; Sífilis/metabolismo; Migración Transendotelial y Transepitelial; Adulto; Moléculas de Adhesión Celular/metabolismo; Comunicación Celular; Células Cultivadas; Femenino; Humanos; Macrófagos/microbiología; Masculino; MicroARNs/metabolismo; Persona de Mediana Edad; Monocitos/metabolismo; Monocitos/fisiología; Células THP-1; Treponema pallidum/patogenicidad; Regulación hacia Arriba

Palabras clave

Endothelial cells; Exosome; JAM-C; Treponema pallidum; miR-146a-5p

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sífilis / Moléculas de Adhesión Celular / MicroARNs / Exosomas / Migración Transendotelial y Transepitelial / Células Endoteliales de la Vena Umbilical Humana / Macrófagos Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Año: 2020 Tipo del documento: Article

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