Large polypoid perineurioma of the transverse colon without crypt serration (NPS).
Int J Clin Exp Pathol
; 11(4): 2088-2091, 2018.
Article
en En
| MEDLINE
| ID: mdl-31938316
ABSTRACT
Intestinal perineuriomas without crypt serration are mainly polypoid lesions characterized by a proliferation of stromal cells expressing perineurial markers. These lesions morphologically differ from those with serrated crypts because of the serrated/hyperplastic architecture in addition to the disorganization of the crypts. These tumors, despite both expression of perineurial cell markers (epithelial membrane antigen, claudin-1, GLUT-1, and collagen type IV), show well-characterized molecular differences such as BRAFV600E mutation, suggesting that they might represent two distinct variants of a single lesion. In this report, we describe a polypoid intestinal perineurioma without crypt serration of the transverse colon, showing an unusual large size compared with other reported polypoid lesions ranging from 0.2 to 0.6 cm in size.
Texto completo:
1
Banco de datos:
MEDLINE
Idioma:
En
Año:
2018
Tipo del documento:
Article