Neutrophilia is associated with a poorer clinical outcome in dogs with chronic hepatitis.
Vet Rec
; 187(6): 234, 2020 09 19.
Article
en En
| MEDLINE
| ID: mdl-31974266
ABSTRACT
BACKGROUND:
Liver disease is a common cause of morbidity and mortality in dogs. Currently, it is challenging to prognosticate in these cases. The aim of this study was to evaluate the utility of the haematological variables in dogs with chronic hepatitis.METHODS:
Dogs with chronic hepatitis confirmed on histopathology had presenting haematological values retrospectively obtained and evaluated against survival time. Eighty-two dogs met the inclusion criteria and their data analysed.RESULTS:
Neutrophilic patients, with a count greater than 12×109/l, controlled for sex and age, had a shorter survival time (P≤0.01). In dogs, neutrophilia at presentation predicted a poor outcome, whereas the other haematological parameters were not prognostically informative. When the dogs were split into even quarters on the basis of their neutrophil count, those within the higher quartiles had poorer survival times. Neutrophilia was associated with a poorer survival time in comparison to those patients with a lower count.CONCLUSION:
The relationship between neutrophils, inflammation and clinical outcome is deserving of future study in dogs with chronic hepatitis.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Enfermedades de los Perros
/
Hepatitis Crónica
/
Trastornos Leucocíticos
/
Neutrófilos
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Límite:
Animals
Idioma:
En
Año:
2020
Tipo del documento:
Article