shRNA-mediated inhibition of PhosphoGlycerate Kinase 1 (PGK1) enhances cytotoxicity of intraperitoneal chemotherapy in peritoneal metastasis of gastric origin.

Archid, Rami; Zieker, Derek; Weinreich, Frank-Jürgen; Hönes, Felix; Königsrainer, Alfred; Quintanilla-Martínez, Leticia; Reymond, Marc A; Solass, Wiebke

Archid, Rami; Zieker, Derek; Weinreich, Frank-Jürgen; Hönes, Felix; Königsrainer, Alfred; Quintanilla-Martínez, Leticia; Reymond, Marc A; Solass, Wiebke.

Afiliación

Archid R; Dept. of General, Visceral and Transplant Surgery, Tübingen, Germany; National Center for Pleura and Peritoneum (NCPP), Tübingen, Germany. Electronic address: rami.archid@med.uni-tuebingen.de.
Zieker D; Dept. of General, Visceral and Transplant Surgery, Tübingen, Germany.
Weinreich FJ; Dept. of General, Visceral and Transplant Surgery, Tübingen, Germany; National Center for Pleura and Peritoneum (NCPP), Tübingen, Germany.
Hönes F; Dept. of General, Visceral and Transplant Surgery, Tübingen, Germany.
Königsrainer A; Dept. of General, Visceral and Transplant Surgery, Tübingen, Germany.
Quintanilla-Martínez L; Institute of Pathology, University of Tübingen, Tübingen, Germany.
Reymond MA; Dept. of General, Visceral and Transplant Surgery, Tübingen, Germany; National Center for Pleura and Peritoneum (NCPP), Tübingen, Germany. Electronic address: marc.reymond@med.uni-tuebingen.de.
Solass W; Institute of Pathology, University of Tübingen, Tübingen, Germany.

Eur J Surg Oncol ; 46(4 Pt A): 613-619, 2020 04.

Article en En | MEDLINE | ID: mdl-31980221

Asunto(s)

Adenocarcinoma/genética; Antineoplásicos/farmacología; Neoplasias Peritoneales/genética; Fosfoglicerato Quinasa/antagonistas & inhibidores; ARN Interferente Pequeño; Neoplasias Gástricas/genética; Carga Tumoral/efectos de los fármacos; Adenocarcinoma/tratamiento farmacológico; Adenocarcinoma/secundario; Animales; Línea Celular Tumoral; Resistencia a Antineoplásicos/genética; Fluorouracilo/farmacología; Técnicas de Silenciamiento del Gen; Humanos; Inyecciones Intraperitoneales; Ratones; Ratones Desnudos; Mitomicina/farmacología; Neoplasias Peritoneales/tratamiento farmacológico; Neoplasias Peritoneales/secundario; Fosfoglicerato Quinasa/genética; Tratamiento con ARN de Interferencia; Neoplasias Gástricas/patología; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

Adenoviral vector; Gastric cancer; Intraperitoneal chemotherapy; Peritoneal metastasis; Phosphoglycerate-kinase 1 (PGK1); shRNA

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Peritoneales / Fosfoglicerato Quinasa / Neoplasias Gástricas / Adenocarcinoma / ARN Interferente Pequeño / Carga Tumoral / Antineoplásicos Tipo de estudio: Clinical_trials Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article

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