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Targeting the NAD+ salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/ß-catenin signaling via increasing Axin level.
Ye, Chenyang; Qi, Lina; Li, Xiaofen; Wang, Ji; Yu, Jiekai; Zhou, Biting; Guo, Cheng; Chen, Jiani; Zheng, Shu.
Afiliación
  • Ye C; Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), the Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, 310009, Hangzhou, China.
  • Qi L; Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), the Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, 310009, Hangzhou, China.
  • Li X; Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), the Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, 310009, Hangzhou, China.
  • Wang J; Department of Abdominal Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
  • Yu J; Department of Surgical Oncology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Zhejiang, 310016, Hangzhou, China.
  • Zhou B; Biomedical Research Center and Key Laboratory of Biotherapy of Zhejiang Province, Zhejiang, 310016, Hangzhou, China.
  • Guo C; Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), the Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, 310009, Hangzhou, China.
  • Chen J; Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), the Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, 310009, Hangzhou, China.
  • Zheng S; Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), the Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, 310009, Hangzhou, China.
Cell Commun Signal ; 18(1): 16, 2020 01 31.
Article en En | MEDLINE | ID: mdl-32005247
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Proteína Axina / Vía de Señalización Wnt / Mutación / NAD Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Proteína Axina / Vía de Señalización Wnt / Mutación / NAD Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2020 Tipo del documento: Article